Protein Alignment Sox15 and SOX7

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_113627.1
• Gene: SOX7 / 83595
• HGNCID: 18196
• Length: 388
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 121/392 - (30%)
• Similarity: 166/392 - (42%)
• Gaps: 131/392 - (33%)

  Fly   201 RPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYV 265
            ||.|.:   ..||||||||||||||||.|||:||.:|||||||:|||||||.|::||...:||||
Human    34 RPPGDK---GSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYV 95

  Fly   266 EEAERLRVIHMTEHPNYKYRPRRRKQSK--LRAMQPG------------------------GKEQ 304
            :||||||:.||.::|||||||||:||:|  .:.:.||                        |:::
Human    96 DEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKE 160

  Fly   305 SESSPNPGT---------------GGSKSNPK--------LATPP-------LATASSSYTTPTD 339
            .....:|||               ||....|.        |.|||       |....:.:::|..
Human   161 DRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQ 225

  Fly   340 ESTCNSTNQNHGQ-----STPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLA----------- 388
            |        .||.     ..||    .|..|.|:||.:.|      :..:.|||
Human   226 E--------EHGHPRRIPHLPG----HPYSPEYAPSPLHC------SHPLGSLALGQSPGVSMMS 272

  Fly   389 --ANCPPALLNESSPTGGGYDNSLL--LKKLTKPSPSRAAKSRQEKLAKSE-----EKNKGSQ-- 442
              ..|||:....|..|.....::|.  |.:|: |.|........::|::.|     ::|:..|
Human   273 PVPGCPPSPAYYSPATYHPLHSNLQAHLGQLS-PPPEHPGFDALDQLSQVELLGDMDRNEFDQYL 336

  Fly   443 ---SQGQSQQGIYAAT--------YPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVS 496
               ....|..|..|.:        .|..||..::::.           |.|    ...|:|...|
Human   337 NTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISV-----------LAD----ATATYYNSYS 386

  Fly   497 VS 498
            ||
Human   387 VS 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	52/70 (74%)
SOX7	NP_113627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..46		6/14 (43%)
		SOX-TCF_HMG-box	44..115	CDD:238684	52/70 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..197		7/56 (13%)
		Sox_C_TAD	198..386	CDD:288887	44/221 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5958
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm40697
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.940