Sequence 1: | NP_523739.2 | Gene: | Sox15 / 36575 | FlyBaseID: | FBgn0005613 | Length: | 784 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001354872.1 | Gene: | TCF7L2 / 6934 | HGNCID: | 11641 | Length: | 619 | Species: | Homo sapiens |
Alignment Length: | 600 | Identity: | 131/600 - (21%) |
---|---|---|---|
Similarity: | 209/600 - (34%) | Gaps: | 193/600 - (32%) |
- Green bases have known domain annotations that are detailed below.
Fly 11 HHLLTNYNSKKYPHV---------------SRTPEYSHSTGS-----DYPEHGGYLTDGRLMHES 55
Fly 56 NSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAY--VGGGTA 118
Fly 119 S------GSLINSN----IPLLGGG----------GNSVLNKFLSH-------------PHAGMV 150
Fly 151 GGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGGTQSKSAKESRI 215
Fly 216 RRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHP 280
Fly 281 NYKYRPR-RRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCN 344
Fly 345 S---TNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGY 406
Fly 407 DNSLLLKKLTKP----SPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVA 467
Fly 468 ARGMY---VTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSM-RNSISALQQHCNVVTSTPSSSG 528
Fly 529 GTMPTSEMSSYTVSM 543 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Sox15 | NP_523739.2 | SOX-TCF_HMG-box | 214..285 | CDD:238684 | 22/70 (31%) |
TCF7L2 | NP_001354872.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..96 | ||
CTNNB1-binding. /evidence=ECO:0000250 | 1..53 | ||||
CTNNB1_binding | 17..259 | CDD:400583 | 27/137 (20%) | ||
Mediates interaction with MAD2L2. /evidence=ECO:0000269|PubMed:19443654 | 201..395 | 52/247 (21%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 318..350 | 8/58 (14%) | |||
SOX-TCF_HMG-box | 353..420 | CDD:238684 | 21/66 (32%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 420..441 | 7/22 (32%) | |||
Nuclear localization signal. /evidence=ECO:0000255 | 425..430 | 1/4 (25%) | |||
Promoter-specific activation domain | 459..505 | 10/80 (13%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..547 | 19/86 (22%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 574..619 | 17/62 (27%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
0 | 0.000 |