Protein Alignment Sox15 and TCF7

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_006714741.1
• Gene: TCF7 / 6932
• HGNCID: 11639
• Length: 460
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 87/398 - (21%)
• Similarity: 145/398 - (36%)
• Gaps: 108/398 - (27%)

  Fly     3 PSYDHEHPHHLLTNYNSKKYPH-VSRTPEYSHSTGSDYPEHGGYLTDGRLMH---ESNSDAGIYH 63
            ||...:||......:.:.:.|| |.:...|.| ..|.:|.........:.:|   ::...:|.|.
Human   134 PSGAGQHPQPQPPLHKANQPPHGVPQLSLYEH-FNSPHPTPAPADISQKQVHRPLQTPDLSGFYS 197

  Fly    64 VRQGS----EHS----SPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVS-SAYVGGGTAS 119
            :..||    .|:    ||.|: |...|.||              ..|.|.|..: .|.....|..
Human   198 LTSGSMGQLPHTVSWPSPPLY-PLSPSCGY--------------RQHFPAPTAAPGAPYPRFTHP 247

  Fly   120 GSLINSNIPLLGGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPN 184
            ..::.|.:|              .||.|             ..|..|               .|.
Human   248 SLMLGSGVP--------------GHPAA-------------IPHPAI---------------VPP 270

  Fly   185 CGYLERHKPLPADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKML 249
            .|..|. :|...:||.:......|.||:..|::|:||||::.|..|.|:..|.....:|.::::|
Human   271 SGKQEL-QPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQIL 334

  Fly   250 GKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRP---RRRKQSKLRAMQPGGKEQSESSPNP 311
            |::|.:|:.:::..|.|.|.:.|.:||..:|.:..|.   :::::|:        ::..||:.:|
Human   335 GRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSR--------EKHQESTTDP 391

  Fly   312 GTGGSKSNPKLATPPLATASSSYTTPTDE-STCNSTNQNH-----------GQSTPGGLYEQPLK 364
            |           :|....|.......||. ..|.....:|           ....|.||...||.
Human   392 G-----------SPKKCRARFGLNQQTDWCGPCRWVCPHHRSPFALSCFPDSAHVPLGLQPTPLA 445

  Fly   365 PTYSPSSV 372
            |  .|:|:
Human   446 P--QPTSI 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	22/70 (31%)
TCF7	XP_006714741.1	CTNNB1_binding	20..212	CDD:285538	17/78 (22%)
		SOX-TCF_HMG-box	300..370	CDD:238684	22/69 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910