Protein Alignment Sox15 and Sox12

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001162121.1
• Gene: Sox12 / 689988
• RGDID: 1586313
• Length: 314
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 82/296 - (27%)
• Similarity: 132/296 - (44%)
• Gaps: 83/296 - (28%)

  Fly   202 PG-GTQSKSAKE--------SRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLT 257
            || |..::.|:|        ..|:|||||||||::.||:|:.|:.||:|||::||.||::|:.|.
  Rat    18 PGPGPAAEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQ 82

  Fly   258 PQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQ---SKLRAMQPGGKEQSESSPNPGTGGSKSN 319
            ..::.|:|.||||||:.||.::|:||||||::.:   :|.|...|||          |.|||:..
  Rat    83 DSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGG----------GGGGSRLK 137

  Fly   320 PKLATP----------PLATASSSYTTPTDES-----------TCNSTNQNHGQSTPGGLYEQ-P 362
            |....|          ||...:::   |.|:.           ...:..:...:..|.|...: |
  Rat   138 PGPQLPGRGGRRATGGPLGGGAAA---PEDDDEDEEEELLEVRLLETPGRELWRMVPAGRAARGP 199

  Fly   363 LKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSR 427
            .:....|||....::|.|            |.|..:..|                       :..
  Rat   200 AERAQGPSSEGAAASAAS------------PTLSEDEEP-----------------------EEE 229

  Fly   428 QEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSV 463
            :|:.|.:||..:.:.:.|:...| :.:..|..||.:
  Rat   230 EEEAATAEEGEEETVASGEEPLG-FLSRMPPGPTGL 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	42/74 (57%)
		PHA03273	305..>391	CDD:223031	18/107 (17%)
Sox12	NP_001162121.1	HMG-box_SF	29..116	CDD:469606	43/86 (50%)