| Sequence 1: | NP_523739.2 | Gene: | Sox15 / 36575 | FlyBaseID: | FBgn0005613 | Length: | 784 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_008872.1 | Gene: | SOX10 / 6663 | HGNCID: | 11190 | Length: | 466 | Species: | Homo sapiens |
| Alignment Length: | 522 | Identity: | 149/522 - (28%) |
|---|---|---|---|
| Similarity: | 215/522 - (41%) | Gaps: | 130/522 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 86 ENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLL---GGGGNSVLNKFLSHPHA 147
Fly 148 GMVGGGTGQMEDCTSHS---PI---EAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGGTQ 206
Fly 207 SKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERL 271
Fly 272 RVIHMTEHPNYKYRPRRRKQSKL---RAMQPGGK-EQSESSP-------------NPGTGG--SK 317
Fly 318 SNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTP---------GGLYEQPLKPTYSPSSVD 373
Fly 374 -------CYSNA---DSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKK-----LTKP----- 418
Fly 419 ---SPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAARGMYVTCNNRGL 480
Fly 481 LDHG-HSVKGTFYPPVSVSEDDNSTSMRNSISAL---QQHCNVVTSTPSSSG--GTMPTS-EMSS 538
Fly 539 YT 540 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sox15 | NP_523739.2 | SOX-TCF_HMG-box | 214..285 | CDD:238684 | 44/70 (63%) |
| SOX10 | NP_008872.1 | Sox_N | 12..93 | CDD:315171 | 25/110 (23%) |
| Dimerization (DIM). /evidence=ECO:0000303|PubMed:31194875 | 62..102 | 11/57 (19%) | |||
| SOX-TCF_HMG-box | 103..173 | CDD:238684 | 43/69 (62%) | ||
| Nuclear export signal | 134..145 | 8/10 (80%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 160..199 | 20/38 (53%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 212..274 | 17/74 (23%) | |||
| Transactivation domain (TAM). /evidence=ECO:0000303|PubMed:31194875 | 228..310 | 21/94 (22%) | |||
| Transactivation domain (TAC). /evidence=ECO:0000303|PubMed:31194875 | 353..466 | 26/115 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 354..375 | 3/20 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 433..466 | 10/29 (34%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..67 | 20/82 (24%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0527 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000028 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||