Protein Alignment Sox15 and SOX4

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_003098.1
• Gene: SOX4 / 6659
• HGNCID: 11200
• Length: 474
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 118/467 - (25%)
• Similarity: 192/467 - (41%)
• Gaps: 108/467 - (23%)

  Fly   202 PGGTQSKSAK----------ESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSL 256
            ||.|.|...|          ...|:|||||||||::|||:|:.:::||:|||::||.|||:|:.|
Human    36 PGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLL 100

  Fly   257 TPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRR--------KQSKLRAMQPGGKEQ----SESSP 309
            ...|:.|::.||||||:.||.::|:||||||::        ..|...:.:||.|..    |....
Human   101 KDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGG 165

  Fly   310 NPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDC 374
            :.|.||..|:........|:...:.:.|..:.:|       |....||......||   .:.:..
Human   166 HGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSC-------GSKVAGGAGGGVSKP---HAKLIL 220

  Fly   375 YSNADSTEQIESLAANC------PPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAK 433
            .......:...:.||:.      ..|||    |.|...|:..|.|..| ||.|.:|.|.....|.
Human   221 AGGGGGGKAAAAAAASFAAEQAGAAALL----PLGAAADHHSLYKART-PSASASASSAASASAA 280

  Fly   434 --------SEEKNK------------------GSQSQGQSQQGIY----AATYPLAP-----TSV 463
                    :|:|.|                  |:.:......|:|    |...|.||     :|.
Human   281 LAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSA 345

  Fly   464 AVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSG 528
            |...|.|       |...||    :|  |..:..:....|::..::.|:...|    :|:.||||
Human   346 ASSPAAG-------RSPADH----RG--YASLRAASPAPSSAPSHASSSASSH----SSSSSSSG 393

  Fly   529 GTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYL---------PSANAYGMQYEDFLRYQSNDM 584
            .:....|.....:.:..:.....:|:...|.:..|         |.:.:: .::.|:...:.::|
Human   394 SSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSH-FEFPDYCTPEVSEM 457

  Fly   585 ---DYSTSAVEH 593
               |:..|::.:
Human   458 ISGDWLESSISN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	39/70 (56%)
SOX4	NP_003098.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		5/21 (24%)
		SOX-TCF_HMG-box	58..129	CDD:238684	39/70 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..228		21/109 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..286		7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..416		25/130 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910