Protein Alignment Sox15 and SOX6

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001139291.2
• Gene: SOX6 / 55553
• HGNCID: 16421
• Length: 828
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 123/593 - (20%)
• Similarity: 190/593 - (32%)
• Gaps: 260/593 - (43%)

  Fly    22 YPHVSRT--------------PEYSHSTGSDYP-------------------------------- 40
            :||..||              |..::..|.:||
Human   272 FPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQIN 336

  Fly    41 -----------------EHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSPSLHSPA--------- 79
                             ||||    |...:....:. :|..:..|...||....|:
Human   337 QRLKGLSDRFGRNLDTFEHGG----GHSYNHKQIEQ-LYAAQLASMQVSPGAKMPSTPQPPNTAG 396

  Fly    80 -IQSSGYENEH-----------------LN------------------EAVLAAHSHSHSPMPMV 108
             :..:|.:||.                 ||                  :.:..|...|...:|..
Human   397 TVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNK 461

  Fly   109 SS--AYVGGGTASGS----LINSNIPLLGGGGNSVLNKF---------------LSHPHA----- 147
            ||  :.:||....||    |.:.|.|.|.|..::|:...               ...||.
Human   462 SSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKL 526

  Fly   148 ----------------------------------GMVGGGTGQM---EDCTSHSPI--EAASMWS 173
                                              |.:|.|...:   ||......:  .||.:..
Human   527 SSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQ 591

  Fly   174 YDYKGDLCAPNCGYLERHKPLPADLK-YRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADEN 237
            |     .|.|..|      ...|:.: ||  ..:.:::.|..|:|||||||||||.||:|:....
Human   592 Y-----YCWPTGG------ATVAEARVYR--DARGRASSEPHIKRPMNAFMVWAKDERRKILQAF 643

  Fly   238 PDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPR--------------- 287
            ||:||:::||:||.:|:|::.|:::||.||..||..||:.::|||||:||
Human   644 PDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIG 708

  Fly   288 ------RRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNST 346
                  |.::.::|.....| :|.:.....|||       :..|...|.:::..:|...|.|:||
Human   709 EYKQLMRSRRQEMRQFFTVG-QQPQIPITTGTG-------VVYPGAITMATTTPSPQMTSDCSST 765

  Fly   347 N-----------QNHGQSTPGGL------------------YEQPLKPTYSPSSVDCYSNADSTE 382
            :           ..:|..|.||.                  ||...|..||          ...|
Human   766 SASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYS----------SENE 820

  Fly   383 QIESLAAN 390
            ..|:::||
Human   821 APEAVSAN 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	38/70 (54%)
SOX6	NP_001139291.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..470		13/89 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	753..828		16/84 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810