Protein Alignment Sox15 and sox9

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001016853.1
• Gene: sox9 / 549607
• XenbaseID: XB-GENE-1034769
• Length: 482
• Species: Xenopus tropicalis
• Alignment Length: 495
• Identity: 137/495 - (27%)
• Similarity: 209/495 - (42%)
• Gaps: 102/495 - (20%)

  Fly   101 SHSPMPMVSSAYVGGGTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSP 165
            |.:|.|.:|....|....|||            |:...|   :.|.......|..:::..|.
 Frog    19 SGAPSPTMSEDSAGSPCPSGS------------GSDTEN---TRPQENTFPKGDPELKKETE--- 65

  Fly   166 IEAASMWSYDYKGDLCAPNC------GYLERHKPLPADLKYRPGGTQSKSAKESRIRRPMNAFMV 224
                     |.|..:|....      ||.....|:|..:.   |.::||    ..::||||||||
 Frog    66 ---------DEKFPVCIREAVSQVLKGYDWTLVPMPVRVN---GSSKSK----PHVKRPMNAFMV 114

  Fly   225 WAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRR 289
            ||:..|:||||:.|.||||:|||.|||.||.|...::||:||||||||:.|..:||:|||:||||
 Frog   115 WAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRIQHKKDHPDYKYQPRRR 179

  Fly   290 KQSKL-RAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQS 353
            |..|. ::.|..|.||:..|||......:::    :|..|::.|...:|.:.|     .|:.|..
 Frog   180 KSVKNGQSEQEDGAEQTHISPNAIFKALQAD----SPHSASSMSEVHSPGEHS-----GQSQGPP 235

  Fly   354 TPGGLYE---QPLKPTY------------SPSSVDCYSNAD----STEQIES------------L 387
            ||....:   ||.||..            .|..:| :.:.|    |:|.|.:            |
 Frog   236 TPPTTPKTDVQPGKPDLKREGRPLQESGRQPPHID-FRDVDIGELSSEVISTIETFDVNEFDQYL 299

  Fly   388 AANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKG----SQSQGQSQ 448
            ..|..|.:.:..:|..|.|..:..........|:..:|.:|::..:.:.....    :..|.|||
 Frog   300 PPNGHPGVGSTQAPYTGSYGINSTPSATPGAGPAWMSKQQQQQQQQPQPPQHSLSTINSEQSQSQ 364

  Fly   449 QGIYAATYPLAPTSVAVVAARGM-----YVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRN 508
            |..:..|..|:|:..:....:..     |.:.|    |.|..|    .||.::.::.| .|..:.
 Frog   365 QRTHIKTEQLSPSHYSDQQQQHSPQQLNYSSFN----LQHYSS----SYPTITRAQYD-YTEHQG 420

  Fly   509 SISALQQHCNVVTSTPSSSGGTMPTSEMSSYTVSMADNCG 548
            | ::...|.:...|...|:...|..|:...|| .:||..|
 Frog   421 S-NSYYSHASGQNSGLYSNFSYMNPSQRPMYT-PIADTTG 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	47/74 (64%)
		PHA03273	305..>391	CDD:223031	23/116 (20%)
sox9	NP_001016853.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66		13/73 (18%)
		Sox_N	22..94	CDD:463586	19/98 (19%)
		Dimerization (DIM). /evidence=ECO:0000250|UniProtKB:P48436	63..103		11/58 (19%)
		PQA. /evidence=ECO:0000250|UniProtKB:P48436	63..103		11/58 (19%)
		HMG-box_SoxE	104..178	CDD:438840	46/73 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..274		37/123 (30%)
		Transactivation domain (TAM). /evidence=ECO:0000250|UniProtKB:P48436	224..308		19/89 (21%)
		9aaTAD 1. /evidence=ECO:0000250|UniProtKB:P48436	276..285		2/8 (25%)
		9aaTAD 2. /evidence=ECO:0000250|UniProtKB:P48436	291..299		0/7 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..395		18/99 (18%)
		Transactivation domain (TAC). /evidence=ECO:0000250|UniProtKB:P48436	366..482		23/104 (22%)
		9aaTAD 3. /evidence=ECO:0000250|UniProtKB:P48436	433..441		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..482		5/12 (42%)