Protein Alignment Sox15 and LEF1

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_005263103.1
• Gene: LEF1 / 51176
• HGNCID: 6551
• Length: 414
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 85/375 - (22%)
• Similarity: 141/375 - (37%)
• Gaps: 113/375 - (30%)

  Fly     2 EPSYD--HEHPHHLLTNYNSKKYPHVSRTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHV 64
            ||.:|  .|||       :..|:|...     .::.|..|..:.||:    :|...|:|.   ::
Human    81 EPYHDKAREHP-------DDGKHPDGG-----LYNKGPSYSSYSGYI----MMPNMNNDP---YM 126

  Fly    65 RQGSEHSSP-----SLHSPAIQSS----------GYENEHLNEAVLAAHSHS----------HSP 104
            ..||  .||     |...|.:|.|          .|.:||.:.....:|..|          |.|
Human   127 SNGS--LSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPP 189

  Fly   105 MPMVSSAY---VGGGTASGSLINSNIPLLGGGGNSV--------------------LNKFLSHPH 146
            .|.:.:.|   .||       :....|.||..|..|                    :::|..|
Human   190 APDIPTFYPLSPGG-------VGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHH-- 245

  Fly   147 AGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKY-RPGGTQSKSA 210
              |:.|..|.......|..|....:                .:.|....:||.: :|...|.|..
Human   246 --MIPGPPGPHTTGIPHPAIVTPQV----------------KQEHPHTDSDLMHVKPQHEQRKEQ 292

  Fly   211 KESR--IRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRV 273
            :..|  |::|:||||::.|..|..:..|.....:|.::::||::|.:|:.:::..|.|.|.:.|.
Human   293 EPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357

  Fly   274 IHMTEHPNYKYR-----PRRRKQSKLRAMQPGGKEQS-------ESSPNP 311
            :||..:|.:..|     .::||:.||:....|||..|       .::|.|
Human   358 LHMQLYPGWSARDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAATPGP 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	22/72 (31%)
LEF1	XP_005263103.1	CTNNB1_binding	1..213	CDD:285538	36/159 (23%)
		SOX-TCF_HMG-box	298..369	CDD:238684	21/70 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910