Protein Alignment Sox15 and Sox21a

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 136/546 - (24%)
• Similarity: 187/546 - (34%)
• Gaps: 209/546 - (38%)

  Fly    51 LMHESNSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGG 115
            |:|.|:|                  ||....|||..|          ||||.|..|.:..
  Fly     7 LLHRSHS------------------HSNGYTSSGSSN----------HSHSSSLSPQLPG----- 38

  Fly   116 GTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGM---VGGGTGQMEDCTSHSPIEAASMWSYDYK 177
                   ||..:.::||.|            .||   ||.|:|.    |:..|:..|
  Fly    39 -------INLGLGMVGGLG------------MGMSVGVGSGSGN----TTPPPMPPA-------- 72

  Fly   178 GDLCAPNCGYLERHKPLP------------------ADLKYRPGGTQSKSAKESRIRRPMNAFMV 224
             ||..|...      |.|                  |...:....|.|.......|:||||||||
  Fly    73 -DLAVPPAA------PTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMV 130

  Fly   225 WAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRR 289
            |::.:|:|:|.:||.:||:::||.||.:|:.||...:||:::||:|||.:||.|||:|||||||:
  Fly   131 WSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK 195

  Fly   290 KQSKLRAMQPGG-------------KEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDES 341
            .::..::..|||             ......:..|...||..:||...|.|:....|..
  Fly   196 PKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLP------ 254

  Fly   342 TCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGY 406
                  ..||..........|..|...|..|             .|||    |.|  |:..|.|.
  Fly   255 ------HLHGHPHQSPYQSHPHHPHPHPHHV-------------QLAA----ATL--SAKYGFGS 294

  Fly   407 DNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAAR-- 469
            ...|.|.:|....|.                               .|.|||.||....:.||
  Fly   295 PLELSLPRLPNAFPG-------------------------------LAHYPLDPTLALDLQARLQ 328

  Fly   470 GMYVTCNNRGLLDHGHSVKGTFY----------------PPVS----VSEDDNSTSMRNSISALQ 514
            .||.               |:.|                ||.|    :|......|.::|.:|:.
  Fly   329 AMYA---------------GSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEKSSPNAVV 378

  Fly   515 QHC----NVVTSTPSSSG-GTMPTSE 535
            ...    |::..||...| ||..::|
  Fly   379 ASAASPPNIIXPTPLRFGAGTSSSAE 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	42/74 (57%)
		PHA03273	305..>391	CDD:223031	17/85 (20%)
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	43/78 (55%)