Protein Alignment Sox15 and Sox21a

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 136/546 - (24%)
• Similarity: 187/546 - (34%)
• Gaps: 209/546 - (38%)

  Fly    51 LMHESNSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGG 115
            |:|.|:|                  ||....|||..|          ||||.|..|.:..
  Fly     7 LLHRSHS------------------HSNGYTSSGSSN----------HSHSSSLSPQLPG----- 38

  Fly   116 GTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGM---VGGGTGQMEDCTSHSPIEAASMWSYDYK 177
                   ||..:.::||.|            .||   ||.|:|.    |:..|:..|
  Fly    39 -------INLGLGMVGGLG------------MGMSVGVGSGSGN----TTPPPMPPA-------- 72

  Fly   178 GDLCAPNCGYLERHKPLP------------------ADLKYRPGGTQSKSAKESRIRRPMNAFMV 224
             ||..|...      |.|                  |...:....|.|.......|:||||||||
  Fly    73 -DLAVPPAA------PTPVAPKMHQHTHHHGNSHHNAPTSHSNSNTGSHHNSHDHIKRPMNAFMV 130

  Fly   225 WAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRR 289
            |::.:|:|:|.:||.:||:::||.||.:|:.||...:||:::||:|||.:||.|||:|||||||:
  Fly   131 WSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRK 195

  Fly   290 KQSKLRAMQPGG-------------KEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDES 341
            .::..::..|||             ......:..|...||..:||...|.|:....|..
  Fly   196 PKTLNKSPVPGGGGGGGGGGANGGVNAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLP------ 254

  Fly   342 TCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGY 406
                  ..||..........|..|...|..|             .|||    |.|  |:..|.|.
  Fly   255 ------HLHGHPHQSPYQSHPHHPHPHPHHV-------------QLAA----ATL--SAKYGFGS 294

  Fly   407 DNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAAR-- 469
            ...|.|.:|....|.                               .|.|||.||....:.||
  Fly   295 PLELSLPRLPNAFPG-------------------------------LAHYPLDPTLALDLQARLQ 328

  Fly   470 GMYVTCNNRGLLDHGHSVKGTFY----------------PPVS----VSEDDNSTSMRNSISALQ 514
            .||.               |:.|                ||.|    :|......|.::|.:|:.
  Fly   329 AMYA---------------GSIYHPWRYLPLISPETPPSPPSSSGTGISSYGCVKSEKSSPNAVV 378

  Fly   515 QHC----NVVTSTPSSSG-GTMPTSE 535
            ...    |::..||...| ||..::|
  Fly   379 ASAASPPNIIXPTPLRFGAGTSSSAE 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	38/70 (54%)
Sox21a	NP_001261827.1	SOX-TCF_HMG-box	120..191	CDD:238684	38/70 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451318
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870