Protein Alignment Sox15 and tcf7

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_031753653.1
• Gene: tcf7 / 395061
• XenbaseID: XB-GENE-855462
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 478
• Identity: 100/478 - (20%)
• Similarity: 177/478 - (37%)
• Gaps: 151/478 - (31%)

  Fly    27 RTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSPSLHSPAIQSSGYENEHLN 91
            |.|| ||      ||......|.:|:::   |....|:..|.:|....::    :.|||.:
 Frog    59 RVPE-SH------PEAMRRTQDAQLVYQ---DKLTDHMEDGVKHQDEGMY----KGSGYPS---- 105

  Fly    92 EAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLL--GGGGNSVL---NKFLSH-PHAGMV 150
                       .|..|:|..|:..|:.|.  ::|.:|::  ..|.:.::   |:..|| .|:..:
 Frog   106 -----------YPFLMLSDPYLSNGSVSA--LSSKVPVVQPSHGVHPLIPYNNESFSHGSHSTHL 157

  Fly   151 GGGTGQMEDCTSHSPIEAASMWSYDYK------GDLC------------APNCGYLERHK----- 192
            .....|.:..  |.|.:.|.:.:: |.      |.:.            .|:||:.:.:.
 Frog   158 PADLNQKQGV--HRPAQTADIPTF-YPLPSGGVGQISPSVGWQSQPVYPIPSCGFRQPYSATLSS 219

  Fly   193 ----------------------PLPA---------------DLKYRPGGTQSKSAKESRIRRPMN 220
                                  |.||               ::|......:.:..|:..|::|:|
 Frog   220 GPSYSRFPHPLMLSPSMHTTGIPHPAIIPHSGNKDIDCYERNMKPHSEPKREREPKKPTIKKPLN 284

  Fly   221 AFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHP----- 280
            |||::.|..|.|:..|.....:|.::::||::|.:|:.:::..|.|.|.:.|.:||..:|
 Frog   285 AFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQSKYYELARKERQLHMQLYPGWSAR 349

  Fly   281 -NYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTD----- 339
             ||..|.||.::           :..:||.:||           :|....|.......||
 Frog   350 DNYGKRKRRTRE-----------KHQDSSSDPG-----------SPKKCRARFGLNQQTDWCGPC 392

  Fly   340 --ESTCNSTNQNHGQ-----STPGGLYEQPLKPTYS----PSSVDCYSNADSTEQIESL--AANC 391
              :..|....|..|:     |:.|...:.|..|..|    |||  .|..|..:...:|:  |.:|
 Frog   393 RRKKKCIRYLQGEGRCGSPVSSDGSAIDSPPSPLNSRHSMPSS--AYPTAKLSSPADSVQSAQSC 455

  Fly   392 PPALLN---ESSPTGGGYDNSLL 411
            .|:..:   .||....||..:.|
 Frog   456 SPSSSSSTVRSSLISPGYKGAFL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	24/76 (32%)
tcf7	XP_031753653.1	CTNNB1_binding	1..196	CDD:400583	35/170 (21%)
		SOX-TCF_HMG-box	279..349	CDD:238684	22/69 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910