Protein Alignment Sox15 and sox2

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_998283.1
• Gene: sox2 / 378723
• ZFINID: ZDB-GENE-030909-1
• Length: 315
• Species: Danio rerio
• Alignment Length: 363
• Identity: 98/363 - (26%)
• Similarity: 161/363 - (44%)
• Gaps: 70/363 - (19%)

  Fly   189 ERHKPLPADLKYRPGGTQSKSAKE----SRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKML 249
            |...|.|.......|.|.|....:    .||:|||||||||::.:|:|:|.|||.:||:::||.|
Zfish     8 ELKPPAPQPNTGGTGNTNSSGNNQKNSPDRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRL 72

  Fly   250 GKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLR---------AMQPGGKEQS 305
            |.:|:.|:..::||:::||:|||.:||.|||:|||||||:.::.::         .:.|||....
Zfish    73 GAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNGMG 137

  Fly   306 ESSPNPGTG-GSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPG-GLYEQPLKPTYS 368
             :....|.| |:..|.::         .||.            ..:|.:..| |:.::.|.....
Zfish   138 -AGVGVGAGLGAGVNQRM---------DSYA------------HMNGWTNGGYGMMQEQLGYPQH 180

  Fly   369 PSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAK 433
            ||     .||.:|.|::.:......||...|......|.|.         ||:.:....|:....
Zfish   181 PS-----LNAHNTAQMQPMHRYDMSALQYNSMTNSQTYMNG---------SPTYSMSYSQQSTPG 231

  Fly   434 SEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVS 498
            ....:.||..:.:|      ::.|...||.:...| |...|.:.|.::        :.|.|.:..
Zfish   232 MTLGSMGSVVKSES------SSSPPVVTSSSHSRA-GQCQTGDLRDMI--------SMYLPGAEV 281

  Fly   499 EDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMPTSEM 536
            :|.::.|..:    :.||........::..||:|.|.|
Zfish   282 QDQSAQSRLH----MSQHYQSAPVPGTTINGTIPLSHM 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	39/70 (56%)
sox2	NP_998283.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		8/32 (25%)
		SOX-TCF_HMG-box	37..108	CDD:238684	39/70 (56%)
		SOXp	107..197	CDD:289133	24/116 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..263		8/34 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..315		4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910