Protein Alignment Sox15 and Sox14

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 742
• Identity: 166/742 - (22%)
• Similarity: 259/742 - (34%)
• Gaps: 250/742 - (33%)

  Fly    12 HLLTNYNSKKYPHVSRTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSP--- 73
            |.|..::....|..|.:|..:.:.|:               .::.|.|.|.|....:..|:|
  Fly    51 HTLPPFSPSPSPASSPSPAPAQTPGA---------------QKTQSQAAITHPAAVASPSAPVAA 100

  Fly    74 ----SLHSPAIQSSGYENEHLNEAVLAAHSHSH----SPMPMVSSAYVGGGTASGSLINSNIPLL 130
                :..:|..:|:     |       .|:|:|    ||.|..|..   .|..|.|.....:.|.
  Fly   101 AAPKTPKTPEPRST-----H-------THTHTHSQHFSPPPRESEM---DGERSPSHSGHEMTLS 150

  Fly   131 GGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLP 195
            ..|.:|           .:|.|        ::..|:.:::.:|
  Fly   151 MDGIDS-----------SLVFG--------SARVPVNSSTPYS---------------------- 174

  Fly   196 ADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQD 260
                   ..|::|......|:|||||||||:::||:|:.:..||||||::||.||::|:.|:..|
  Fly   175 -------DATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDD 232

  Fly   261 RRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATP 325
            ::||:.|||:||.:||.|:|||||||::::.....:::|........:.|..|..:.|...||..
  Fly   233 KQPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAIN 297

  Fly   326 PLATASSSYTTPTDESTCNS------TNQNHGQSTPGGLYEQPLKPTYSPSSVD----------- 373
            ...||.......|  |||.|      ...:.|.::....||..::.....:|.|
  Fly   298 GTTTAGRKSKRST--STCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLIS 360

  Fly   374 ----------CYSNADSTEQIESLAANCP---------------PALL----------------- 396
                      ..||||..|::.|..::.|               |..|
  Fly   361 YQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQ 425

  Fly   397 -NESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAP 460
             |:|.||.|..||      ::..||....:...|::.:                  |.....:.|
  Fly   426 HNQSDPTAGLMDN------ISDISPINDREELTEEVMR------------------YLPYLEVNP 466

  Fly   461 TSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQ---------H 516
            :|      .|:.:...:..||  |..:.    .||..|| ||..:..|..||..|         .
  Fly   467 SS------DGLTLKVESSSLL--GKPLN----EPVFDSE-DNIVNDANLHSASHQIPPYVPDSHD 518

  Fly   517 CNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFLRYQS 581
            |........||...:....:...||:|...|              .||    ||........:|:
  Fly   519 CFAEDCGGDSSSHQVEFEVVRPQTVTMTMTC--------------TLP----YGGPDAGHTTFQA 565

  Fly   582 NDMDYSTSAVEHKE----TTSDS--------------ASGQKCLKYPDTNQNYD----------D 618
            :|.:...||.|..|    |||:|              |.|..|..   ..|:|.          :
  Fly   566 DDFNAIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTY---AQQDYTGSVIETHNDLN 627

  Fly   619 YEAEAYSNAMLPATAASYYTQLPYPPT 645
            |.|...:.|:|..|    :..||..||
  Fly   628 YAAHDNNGALLAYT----FEDLPPQPT 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	43/74 (58%)
		PHA03273	305..>391	CDD:223031	23/112 (21%)
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	43/74 (58%)