Protein Alignment Sox15 and sox17

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_571362.2
• Gene: sox17 / 30544
• ZFINID: ZDB-GENE-991213-1
• Length: 413
• Species: Danio rerio
• Alignment Length: 544
• Identity: 152/544 - (27%)
• Similarity: 207/544 - (38%)
• Gaps: 185/544 - (34%)

  Fly   142 LSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAP---NCGYLERHKPLPADLKYR-- 201
            :|.|.||.......|...|:|                 :..|   .|.:::...|| :|.|.:
Zfish     1 MSSPDAGYSSDDPSQTSSCSS-----------------VMMPGMGQCPWVDPLSPL-SDSKSKHE 47

  Fly   202 ------PGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQD 260
                  ||    :...|.||||||||||||||.|||:||.:|||||||:|||||||.|::|...|
Zfish    48 KCSAAGPG----RGKSEPRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALPMVD 108

  Fly   261 RRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATP 325
            :||:|||||||||.||.:|||||||||||||.|      ..|....|.|.||...:|..  |.|.
Zfish   109 KRPFVEEAERLRVKHMQDHPNYKYRPRRRKQVK------RNKRLEPSFPLPGMCDAKMT--LCTE 165

  Fly   326 PLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAAN 390
            .::...|....|   ..|    :||      .|:|....||..||.:|    |.:||....|
Zfish   166 GMSAGYSGAGLP---QYC----ENH------TLFESYSLPTPDPSPMD----AGTTEFFAQL--- 210

  Fly   391 CPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAAT 455
                                                 |::.|.|....:  :...|.|..|...|
Zfish   211 -------------------------------------QDQSAFSYHHQQ--EHHFQEQTNILNDT 236

  Fly   456 YPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNS-ISA--LQQ-- 515
            :           ..|...|..:|    ..||:.   |..::.:.:.|..:..|: :|:  |||
Zfish   237 H-----------CHGNTQTLKSR----QSHSIA---YSNINTNTNSNLHAPINAQLSSINLQQVF 283

  Fly   516 --------------HCNVVTSTPSSSGGTMPTSEMSSYTVSMAD-NC-GNLRLSMNELSGNEYLP 564
                          |.|:...:||||         |.:.::.|. || ..|....|..|
Zfish   284 HENANPQISHHPGTHLNIFNRSPSSS---------SHHAMTPAYLNCPSTLDTFYNSSS------ 333

  Fly   565 SANAYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEAE-----AY 624
                           |..::.:..|:..||:.:...|..|.......:.|..|:.|.|     ..
Zfish   334 ---------------QMKELSHCVSSHTHKQQSIAEAQSQASTATHSSGQMVDEVEFEHCLSFGV 383

  Fly   625 SNAMLP-----------ATAASYY 637
            .:|.||           |::|.||
Zfish   384 PSAPLPGSDLISTVLSDASSAVYY 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	54/70 (77%)
sox17	NP_571362.2	SOX-TCF_HMG-box	62..133	CDD:238684	54/70 (77%)
		Sox_C_TAD	186..411	CDD:288887	59/316 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5813
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm24659
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.040