Protein Alignment Sox15 and Sox8

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001100459.1
• Gene: Sox8 / 302993
• RGDID: 1309072
• Length: 463
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 154/585 - (26%)
• Similarity: 212/585 - (36%)
• Gaps: 193/585 - (32%)

  Fly   151 GGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNC------GYLERHKPLPADLKYRPGGTQSKS 209
            |||.|        ...|||     |.:...|..:.      ||.....|:|.    |.||..:..
  Rat    47 GGGRG--------DTAEAA-----DERFPACIRDAVSQVLKGYDWSLVPMPV----RGGGGGTLK 94

  Fly   210 AKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVI 274
            || ..::||||||||||:..|:||||:.|.||||:|||.|||.||.|:..::||:|||||||||.
  Rat    95 AK-PHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQ 158

  Fly   275 HMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTD 339
            |..:||:|||:|||||..|.      |:..|:|....|
  Rat   159 HKKDHPDYKYQPRRRKSVKT------GRSDSDSGTELG--------------------------- 190

  Fly   340 ESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSV--DCYSNADSTEQIESLAANCPPALLNESSPT 402
                     :|    |||       |.|...:|  |.:.::|.|.|...     ||
  Rat   191 ---------HH----PGG-------PMYKTDTVLGDAHRHSDHTGQTHG-----PP--------- 221

  Fly   403 GGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVA 467
                         |.|:..:....:....:|.|.:.:|.:.....:|.|..:...::..|..|:
  Rat   222 -------------TPPTTPKTDLHQASNGSKQELRLEGRRLVDSGRQNIDFSNVDISELSSEVI- 272

  Fly   468 ARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMP 532
                              |...||    .|.|.|....: |..|||....:..|::.|..|
  Rat   273 ------------------SNMDTF----DVHEFDQYLPL-NGHSALATEPSQATASGSYGG---- 310

  Fly   533 TSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFLRYQSNDMDYSTSAVEHKETT 597
                :||:.|.|...|     .:.:..::..|||:|...:... ||........|.|   |....
  Rat   311 ----ASYSHSGATGIG-----ASPVWAHKGAPSASASPTEAGP-LRPHIKTEQLSPS---HYNDQ 362

  Fly   598 SDSASGQKCLKYPDTNQNYDDYEAEAYSNAMLPATAASYYTQLPYPPTSLAAFPLQLAVPFQQTT 662
            |..:.|:         .:|..|.|:|.......|||||.:.......|.|.|
  Rat   363 SHGSPGR---------ADYGSYSAQASVTTAASATAASSFASAQCDYTDLQA------------- 405

  Fly   663 SGAYGAQPIQSGYLHYGNYGGYEGMAQSQPQN--QAPVHHQQA---SHSAPPSLSVPPNQTVTSN 722
                      |.|  |..|.||       |.:  |.|..|...   :.|....||:||..:.:||
  Rat   406 ----------SNY--YSPYPGY-------PPSLYQYPYFHSSRRPYASSLLNGLSMPPAHSPSSN 451

  Fly   723  722
              Rat   452  451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	45/70 (64%)
Sox8	NP_001100459.1	Sox_N	18..86	CDD:403592	13/55 (24%)
		SOX-TCF_HMG-box	98..168	CDD:238684	44/69 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810