Protein Alignment Sox15 and Tcf7l1

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001073290.1
• Gene: Tcf7l1 / 21415
• MGIID: 1202876
• Length: 599
• Species: Mus musculus
• Alignment Length: 496
• Identity: 104/496 - (20%)
• Similarity: 169/496 - (34%)
• Gaps: 156/496 - (31%)

  Fly     8 EHPHHL-----LTNYNSKKY----PHVSRTPEYSHSTGSDYPEHGGYLTD---------GRLMHE 54
            :||||:     |..|::..:    |....:||....||...|.|...|:.         |::.|.
Mouse   195 QHPHHMHPLTPLITYSNDHFSPASPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHP 259

  Fly    55 -----SNSDAGIYHVRQGS-EHSSPSLHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYV 113
                 ......:|.:..|. .|..|:|...|..||           |.:....|    ||:.|:.
Mouse   260 LGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSS-----------LVSSRFPH----MVAPAHP 309

  Fly   114 GGGTASGSLINSNIPLLGGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKG 178
            |            :|..|            .||..:|             |||         .|.
Mouse   310 G------------LPTSG------------IPHPAIV-------------SPI---------VKQ 328

  Fly   179 DLCAPNCGYLERHKPLPADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNA 243
            :..||:..        ||.....|...:.:..|:..:::|:||||::.|..|.|:..|.....:|
Mouse   329 EPAAPSLS--------PAVSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESA 385

  Fly   244 DLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHP------NYKYRPRRRKQSKLRAMQPGGK 302
            .::::||:||.:|:.:::..|.|.|.:.|.:|...:|      ||..:.:|:::.:|...|
Mouse   386 AINQILGRKWHNLSREEQAKYYELARKERQLHAQLYPTWSARDNYGKKKKRKREKQLSQTQ---- 446

  Fly   303 EQSESSPNPGTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQ-----STPGGLYEQP 362
            .|.:.....|...|||.....         .|..|  |..|:|...:||.     :||......|
Mouse   447 SQQQIQEAEGALASKSKKPCI---------QYLPP--EKPCDSPASSHGSTLDSPATPSAALASP 500

  Fly   363 LKPTYSPSSVDCYSNADSTEQIESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSR 427
            ..|.           |..:||.:.|:..                         |||. :||..:.
Mouse   501 AAPA-----------ATHSEQAQPLSLT-------------------------TKPE-ARAQLAL 528

  Fly   428 QEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAA 468
            ......|.:....:.||..||..:.:...||.....|::.:
Mouse   529 HSAAFLSAKAAASNSSQMGSQPPLLSRPLPLGSMPAALLTS 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	23/76 (30%)
Tcf7l1	NP_001073290.1	CTNNB1_binding	28..262	CDD:285538	16/66 (24%)
		SOX-TCF_HMG-box	356..427	CDD:238684	21/70 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000