Protein Alignment Sox15 and Sox2

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_035573.3
• Gene: Sox2 / 20674
• MGIID: 98364
• Length: 319
• Species: Mus musculus
• Alignment Length: 273
• Identity: 84/273 - (30%)
• Similarity: 134/273 - (49%)
• Gaps: 60/273 - (21%)

  Fly   203 GGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEE 267
            ||.|..|  ..|::|||||||||::.:|:|:|.|||.:||:::||.||.:|:.|:..::||:::|
Mouse    33 GGNQKNS--PDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDE 95

  Fly   268 AERLRVIHMTEHPNYKYRPRRRKQSKLR---------AMQPGGKEQSESSPNPGTG-GSKSNPKL 322
            |:|||.:||.|||:|||||||:.::.::         .:.|||...: |....|.| |:..|.::
Mouse    96 AKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMA-SGVGVGAGLGAGVNQRM 159

  Fly   323 ATPPLAT--ASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPL---------------------- 363
            .:.....  ::.||:...::.   ...|:.|.:..|....||:
Mouse   160 DSYAHMNGWSNGSYSMMQEQL---GYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNG 221

  Fly   364 KPTYSPSSVDCYSNADST--------EQIESLAANCPPALLNES---SPTGGGYDN---SLLLKK 414
            .||||.|    ||...:.        ..::|.|::.||.:.:.|   :|...|...   |:.|..
Mouse   222 SPTYSMS----YSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPG 282

  Fly   415 LTKPSPSRAAKSR 427
            ...|.|  ||.||
Mouse   283 AEVPEP--AAPSR 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	38/70 (54%)
Sox2	NP_035573.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		4/11 (36%)
		SOX-TCF_HMG-box	42..113	CDD:238684	38/70 (54%)
		SOXp	112..202	CDD:403523	20/93 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..267		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..319

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910