Protein Alignment Sox15 and Sox15

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_033261.1
• Gene: Sox15 / 20670
• MGIID: 98363
• Length: 231
• Species: Mus musculus
• Alignment Length: 214
• Identity: 72/214 - (33%)
• Similarity: 113/214 - (52%)
• Gaps: 35/214 - (16%)

  Fly   202 PGGTQSKSAKES----------RIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSL 256
            |.|.|.:.|..|          :::|||||||||:.::|:::|.:||.:||:::||.||.:|:.|
Mouse    24 PLGPQEQEAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLL 88

  Fly   257 TPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQP-----GGKEQSESSPNPG---T 313
            ..:::||:||||:|||..|:.::|:|||||||:.::......|     ||.....|...||   |
Mouse    89 GDEEKRPFVEEAKRLRARHLRDYPDYKYRPRRKSKNSSTGSVPFSQEGGGLACGGSHWGPGYTTT 153

  Fly   314 GGSK----SNPKLATPPL-ATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVD 373
            .||:    ..|..:|..| .:.:||:..|.....|     ...||.|  ..:..|:|::||
Mouse   154 QGSRGFGYQPPNYSTAYLPGSYTSSHCRPEAPLPC-----TFPQSDP--RLQGELRPSFSP---- 207

  Fly   374 CYSNADSTEQIESLAANCP 392
             |.:.||:....:..|..|
Mouse   208 -YLSPDSSTPYNTSLAGAP 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	38/74 (51%)
		PHA03273	305..>391	CDD:223031	24/93 (26%)
Sox15	NP_033261.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		10/30 (33%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000269|PubMed:16759287	1..45		10/30 (33%)
		HMG-box_SoxA_SoxB_SoxG	46..121	CDD:438837	32/74 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..136		6/32 (19%)
		Interaction with FHL3. /evidence=ECO:0000269|PubMed:17363903	136..181		12/49 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..231		8/29 (28%)