Protein Alignment Sox15 and Sox1

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_033259.2
• Gene: Sox1 / 20664
• MGIID: 98357
• Length: 391
• Species: Mus musculus
• Alignment Length: 520
• Identity: 111/520 - (21%)
• Similarity: 176/520 - (33%)
• Gaps: 196/520 - (37%)

  Fly    75 LHSPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLLGGGGNSVLN 139
            ||||                    ..:.:|..:...|..|||              ||||.
Mouse    10 LHSP--------------------GGAQAPTNLSGPAGAGGG--------------GGGGG---- 36

  Fly   140 KFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGG 204
                       |||.|                                               ||
Mouse    37 -----------GGGGG-----------------------------------------------GG 43

  Fly   205 TQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAE 269
            |:   |.:.|::|||||||||::.:|:|:|.|||.:||:::||.||.:|:.::..::||:::||:
Mouse    44 TK---ANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAK 105

  Fly   270 RLRVIHMTEHPNYKYRPRRRKQSKLR------------AMQPGGKEQSESSPNPGTGGSKSNPKL 322
            |||.:||.|||:|||||||:.::.|:            |...||..........|.|.:....:|
Mouse   106 RLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRL 170

  Fly   323 ATP---------------------PLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKP- 365
            .:|                     .:|.|:::.....:.......:...|.:.|   :..|..|
Mouse   171 ESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHP---HAHPAHPH 232

  Fly   366 ----------------------TYSP-SSVDCYSNADSTEQIESLAANCP-PALLNESSPTGGGY 406
                                  .||| |:...|.:|.     .|.....| .|....::..||.:
Mouse   233 PHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSAS-----PSGYGGIPYGAAAAAAAAAGGAH 292

  Fly   407 DNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAPTSVAVVAARGM 471
            .||.:.......:.|..|......|.|||.  .||..         |..:..||....:.....|
Mouse   293 QNSAVAAAAAAAAASSGALGALGSLVKSEP--SGSPP---------APAHSRAPCPGDLREMISM 346

  Fly   472 YVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMPTSEM 536
            |:.....|             .|.:.:    :.:.::.:.:|.||   .....:...||:|.:.:
Mouse   347 YLPAGEGG-------------DPAAAA----AAAAQSRLHSLPQH---YQGAGAGVNGTVPLTHI 391

  Fly   537  536
            Mouse   392  391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	41/74 (55%)
		PHA03273	305..>391	CDD:223031	17/130 (13%)
Sox1	NP_033259.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		22/140 (16%)
		HMG-box_SoxB	49..128	CDD:438790	42/78 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		4/37 (11%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	342..350		2/7 (29%)