Protein Alignment Sox15 and gei-3

DIOPT Version :10

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001076772.1
• Gene: gei-3 / 184597
• WormBaseID: WBGene00001560
• Length: 1405
• Species: Caenorhabditis elegans
• Alignment Length: 700
• Identity: 150/700 - (21%)
• Similarity: 233/700 - (33%)
• Gaps: 187/700 - (26%)

  Fly    27 RTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGI-YHV--RQGSEHSSPSLHSPAIQSSGYENE 88
            :|.|.|.....|....||.||.....:.:.|.:.. .|.  |.|..:.:|:       |.|.:|:
 Worm   691 KTEERSDDDDDDSSGGGGGLTSTGSSNPNGSSSNFQIHTTSRSGESNVTPT-------SGGDQNQ 748

  Fly    89 HLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSL----INSNIPLLGGGGNSVLNKFLSHPHAGM 149
            :       ..|:|.:     |||.:.|...|..|    .::..|.|....:|:
 Worm   749 N-------QQSNSRN-----SSAELAGCDMSQELSVETSDAGPPTLPSQPSSI------------ 789

  Fly   150 VGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGGTQSK------ 208
                 |...:....||::             ..||..|.:.......|:|  |...||.
 Worm   790 -----GSSVNSAFRSPVK-------------IEPNDDYEQSSVKDVMDVK--PEVFQSAKERRRS 834

  Fly   209 --SAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERL 271
              ||.|..:||||||||:::|..|..:..:.|:..|..:||:||:.|.||....:..|.:.|.::
 Worm   835 KVSANEPHVRRPMNAFMIFSKRHRPLVHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQV 899

  Fly   272 RVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATPPLATASSSYTT 336
            :..|...||::|:   ..|:.|:::      |...::|            :|..||......:..
 Worm   900 KEAHFKAHPDWKW---STKEKKIKS------ESLNTTP------------VALTPLKNKVFDFDI 943

  Fly   337 PTDESTCNSTNQNHGQSTPGGLYEQPLKP-TYSPSSVDCYSNADSTEQIES---------LAANC 391
            .|.:....|       ...|.....|:.| |...|:....|:.|||:...|         ::.:.
 Worm   944 RTSDDLAKS-------FVDGTALLSPMTPMTPGASAFRHLSSRDSTQSSTSSFDFPGLPLMSPSL 1001

  Fly   392 PPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATY 456
            ....:|.:|.|             :.|:.|.|..|.|...          :|..|...|:|....
 Worm  1002 SAISMNTASIT-------------SSPALSSATPSFQFDF----------ESLKQGTAGVYPTFN 1043

  Fly   457 P-----LAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQH 516
            |     |..:|........||.|           .:...|.|..|.....|.|.  :||......
 Worm  1044 PAMISTLVNSSTPCRQILPMYNT-----------DISSFFLPTASAFRVLNPTI--SSIIGGFSS 1095

  Fly   517 CNVVTSTPSSSGGTMPTSEMS-SYTVSMADNCGNLRLSMNELS------GNEYLPSAN------- 567
            .:.||:...:...||...:|| ..|.||.........|::.|.      |...|||.|
 Worm  1096 ADTVTTPLGAPATTMAAMKMSFPETASMLPQLQEKLESVSFLDQIKIEPGETPLPSPNVVRPTII 1160

  Fly   568 ------AYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEA----- 621
                  |...|:  .|:.....:....:....:|..:|.....|..|..|  :..|...|
 Worm  1161 PTAQFLAPTQQF--VLQPTPAQLGIRRNKRPLREIDTDVTVSAKLFKRND--EQMDKLLARVGFT 1221

  Fly   622 EAYSNAMLPATAASYYTQLPYPPTSLAAFPLQLAVPFQ---QTTSGAYGA 668
            |.:  |.||......|.::|..|        .|..||:   |..|..:||
 Worm  1222 EKF--AQLPEFTPKIYNEIPASP--------NLPTPFKTPGQDQSIFFGA 1261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	25/74 (34%)
		PHA03273	305..>391	CDD:223031	16/95 (17%)
gei-3	NP_001076772.1	DUF4819	194..275	CDD:465014
		HMG-box_CIC-like	842..918	CDD:438806	26/78 (33%)