Protein Alignment Sox15 and sox-2

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_741836.1
• Gene: sox-2 / 181002
• WormBaseID: WBGene00004949
• Length: 283
• Species: Caenorhabditis elegans
• Alignment Length: 294
• Identity: 94/294 - (31%)
• Similarity: 137/294 - (46%)
• Gaps: 83/294 - (28%)

  Fly   149 MVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKP-----------LPADLKYRP 202
            |:...:.:|:|         .|.||:.:              |.|           :|.||...|
 Worm     2 MMDPDSAKMQD---------YSGWSFGF--------------HMPPTSSTNLLPQSMPDDLSNGP 43

  Fly   203 GGTQS--KSAK--ESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRP 263
            ....|  |..|  :.|::|||||||||::.:|||:|.|||.:||:::||.||.:|:.|:.|::||
 Worm    44 DSPDSTGKDGKKNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRP 108

  Fly   264 YVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATP--- 325
            :::||:|||.|||.|||:|||||||:.:|                         .|.|...|
 Worm   109 FIDEAKRLRAIHMKEHPDYKYRPRRKTKS-------------------------INKKNGAPIPF 148

  Fly   326 -PLATASSSYTTPTDESTCNSTNQNHGQ------STPGGLYEQPLKPTYSPSSVDCYSNADSTEQ 383
             .|.|.:.||  ||..:..|:|||...|      .|...:.:.|...||...||...:::.|..|
 Worm   149 GNLDTKTPSY--PTLTTNWNATNQYIDQFRFAPYPTTTVMDQIPFSLTYPVHSVPTDNSSPSQFQ 211

  Fly   384 IESLAANCPPALL---NESSPTG-----GGYDNS 409
            ...::.|...:.|   :||||.|     |..|:|
 Worm   212 PSPMSTNFAGSYLTPKSESSPVGSDSTVGTVDSS 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	41/70 (59%)
sox-2	NP_741836.1	SOX-TCF_HMG-box	59..130	CDD:238684	41/70 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040