Protein Alignment Sox15 and sem-2

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 109/408 - (26%)
• Similarity: 169/408 - (41%)
• Gaps: 96/408 - (23%)

  Fly   150 VGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLPADLKYRPGGTQSKSAKESR 214
            |...|....:.||.:.:..:....:...|....   ||....:.:|..:......|..|.: .:.
 Worm    32 VASSTSGATNATSSNSVATSQQLQHHPYGTAAG---GYKHAQQAIPKSVTPYSDATNCKKS-SNH 92

  Fly   215 IRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEH 279
            |:|||||||||:::||:|:.:..||:|||::||.||.:|||||.:::.|:|.|||||||.||.|:
 Worm    93 IKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAERLRVCHMQEY 157

  Fly   280 PNYKYRPRRRKQSKLRAMQPGGKEQSESSPN-------PGTGGSKSNPKLATPPLATASSSY--- 334
            |:|||:||::.:.     .|.|..|..:.|.       |..|.|....:...|.....|.:.
 Worm   158 PDYKYKPRKKPKK-----NPDGTLQQPAQPQAPQQQQAPPRGASPQARQRKRPNTDQQSETQQFQ 217

  Fly   335 ---TTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTY-SPSSVDCYSNADSTEQIESLAANCPPAL 395
               :...::....:.:.:|.|       :.|..|:| |||.   :.:|..|
 Worm   218 NFKSVKVEQDWMGNAHMSHAQ-------KMPFHPSYPSPSE---FGHAPLT-------------- 258

  Fly   396 LNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAP 460
                 |..|.||:..            ..:..|:..|.....:.||               ||..
 Worm   259 -----PESGFYDDYF------------TQQHHQQHFASQHHNSAGS---------------PLRM 291

  Fly   461 TSVAVVAARGMYVTCNNRGLLDHGHSVKGTFY---PPVSVSEDD-NSTSMRNS----ISALQQHC 517
            |::.:.......:..:|.|.....|    .||   .|.||.:|| .|.|..:|    .||.:|.
 Worm   292 TNLGMDMGMPPQMMGHNSGFGAGNH----PFYLHTSPPSVDQDDMRSLSSGSSGYADCSASEQS- 351

  Fly   518 NVVTSTPSSSG-GTMPTS 534
               ||:|:|:| .||.|:
 Worm   352 ---TSSPNSAGVVTMATA 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	42/70 (60%)
sem-2	NP_740846.1	SOX-TCF_HMG-box	92..159	CDD:238684	39/66 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940