Protein Alignment Sox15 and sox10

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_571950.1
• Gene: sox10 / 140616
• ZFINID: ZDB-GENE-011207-1
• Length: 485
• Species: Danio rerio
• Alignment Length: 679
• Identity: 162/679 - (23%)
• Similarity: 243/679 - (35%)
• Gaps: 231/679 - (34%)

  Fly    69 EHSSPSLH-SPAIQSSGYENEHLNEAVLAAHSHSHSPMPMVSSAYVGGGTASGSLINSNIPLLG- 131
            |||...:. ||.:...|               ||.||           |.:||:...::.||.|
Zfish     5 EHSMSEVEMSPGVSDDG---------------HSMSP-----------GHSSGAPGGADSPLPGQ 43

  Fly   132 -----GGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPI---EAASMWSYDYKGDLCAPNCGYL 188
                 |.|:.         .||:.||.:.:.::.....||   ||.|.....|...|.
Zfish    44 QSQMSGIGDD---------GAGVSGGVSVKSDEEDDRFPIGIREAVSQVLNGYDWTLV------- 92

  Fly   189 ERHKPLPADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKW 253
                |:|..:.   .|::||    ..::||||||||||:..|:||||:.|.||||:|||.|||.|
Zfish    93 ----PMPVRVN---SGSKSK----PHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLW 146

  Fly   254 RSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKS 318
            |.|...|:||::|||||||..|..::|.|||:|||||..|     ||...::::........|:|
Zfish   147 RLLNETDKRPFIEEAERLRKQHKKDYPEYKYQPRRRKNGK-----PGSSSEADAHSEGEVSHSQS 206

  Fly   319 NPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQ 383
            :.|                          ..|.:...||....||...:.|.:
Zfish   207 HYK--------------------------SLHLEVAHGGAAGSPLGDGHHPHA------------ 233

  Fly   384 IESLAANCPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQ 448
                              ||..:         :.|:|....|:..:.....|.|.:|    |.|:
Zfish   234 ------------------TGQSH---------SPPTPPTTPKTELQGGKSGEGKREG----GASR 267

  Fly   449 QGIYAATYPLAPTSVAVVAARGM-YVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISA 512
            .|:...    |..|.|..:|.|. ::...|..:.:..|.|.... .|..|:|.|         ..
Zfish   268 SGLGVG----ADGSSASSSASGKPHIDFGNVDIGEISHDVMANM-EPFDVNEFD---------QY 318

  Fly   513 LQQHCNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFL 577
            |..:.:...|..:|:|...|     |||..::.       ::...||
Zfish   319 LPPNGHPQASATASAGSAAP-----SYTYGISS-------ALAAASG------------------ 353

  Fly   578 RYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEAEAYSNAMLPATAASYYTQLPY 642
                    :||:.:..::..|....|.            |..:.:..|....|...|:..:.:.|
Zfish   354 --------HSTAWLSKQQLPSQQHLGA------------DGGKTQIKSETHFPGDTAASGSHVTY 398

  Fly   643 PPTSL----AAFP-----LQLAVPFQQTTSGAYGAQPIQSGYLHYGNYGGYEGMAQSQ------- 691
            .|.:|    :|||     .|.|...:...||:|.|...|:.    |.|..:..|..||
Zfish   399 TPLTLPHYSSAFPSLASRAQFAEYAEHQASGSYYAHSSQTS----GLYSAFSYMGPSQRPLYTAI 459

  Fly   692 ------PQNQAPVHHQQASHSAPPSLSVP 714
                  ||:.:|.|.:|..::   :||.|
Zfish   460 PDPGSVPQSHSPTHWEQPVYT---TLSRP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	43/70 (61%)
sox10	NP_571950.1	Sox_N	13..97	CDD:289229	28/129 (22%)
		SOX-TCF_HMG-box	107..177	CDD:238684	42/69 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810