DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox15 and sox32

DIOPT Version :9

Sequence 1:	NP_523739.2	Gene:	Sox15 / 36575	FlyBaseID:	FBgn0005613	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_571926.1	Gene:	sox32 / 116990	ZFINID:	ZDB-GENE-011026-1	Length:	307	Species:	Danio rerio

Alignment Length:	239	Identity:	86/239 - (35%)
Similarity:	116/239 - (48%)	Gaps:	68/239 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 CGYLER---------HKPLPADLKYRPGGTQS-------KSAKESRIRRPMNAFMVWAKIERKKL 233
            |.||:.         |.|....|.....|::|       |:..|:|:|||:|||::|.|.||::|
Zfish    24 CHYLQHQNDEQRRTAHCPASGPLSPVSVGSESSCSSPEAKAPVETRVRRPLNAFIIWTKEERRRL 88

  Fly   234 ADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQ 298
            |..||||.|.||||:|||.|::::..|:|||::||||||:.|..::|||||||||||.:|..:..
Zfish    89 AQLNPDLENTDLSKILGKTWKAMSLADKRPYMQEAERLRIQHTIDYPNYKYRPRRRKCNKRSSKM 153

  Fly   299 PGGKEQSESSPN--------------------------PGTGGSKSNPKLATPPLATASSSYTTP 337
            |  ..::.||||                          |..|.|..|          .||||..
Zfish   154 P--SSENVSSPNATFDLSYMFQGQAPQRPYNQINSYRLPHNGFSFEN----------HSSSYHF- 205

  Fly   338 TDESTCNSTNQNHGQST---------PGGLYEQPLKPTYSPSSV 372
              |:|.:|.|..||.:|         |...|.:.|  .||..||
Zfish   206 --EATSSSGNVFHGGATSMNLSNVHLPRSAYSESL--LYSQHSV 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	41/70 (59%)
sox32	NP_571926.1	SOX-TCF_HMG-box	69..140	CDD:238684	41/70 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940