Protein Alignment Sox15 and sox17b.2

DIOPT Version :9

• Sequence 1: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001090837.1
• Gene: sox17b.2 / 100038235
• XenbaseID: XB-GENE-495335
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 131/479 - (27%)
• Similarity: 184/479 - (38%)
• Gaps: 162/479 - (33%)

  Fly   186 GYLERHKPL----PADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLS 246
            |..|...||    .|..|...|...|:...|:||||||||||||||.|||:||.:|||||||:||
 Frog     3 GQYEWTDPLTMFQDAKTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELS 67

  Fly   247 KMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNP 311
            |||||.|:|||...:||:|:|||||||.|:.::|:|||||||:||.|   .:..|...|...|.|
 Frog    68 KMLGKSWKSLTLASKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVK---REEEGFLPSADIPGP 129

  Fly   312 GTGGSKSNPKLATPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYE--QPLKPTYSPSSVDC 374
            ...|..          |....:|     :...:..|....|.||.|.:|  .|:...|...:|..
 Frog   130 QVMGCN----------AMVGQNY-----KMQYSGQNSQQSQITPAGYFEDHNPVGFYYRGYNVPK 179

  Fly   375 YSNADSTEQIESLAANCPPALLNESSPTGGGYD------NSLLL---KKLTKPSPSRAAKSRQEK 430
            |..:.::      :..|.|       ||.|.|.      ||..:   :..:.|:..:....::..
 Frog   180 YYMSQNS------SGYCSP-------PTQGEYQALSYNFNSSYIPYQQNASAPAMGKQMAVKENI 231

  Fly   431 LAKSEEKN-KGSQSQGQSQQG-IY----AATYPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKG 489
            :.:|.|.. .|.|...|...| :|    |.|:|:|.|.                   .|
 Frog   232 IQESPEHGIMGCQVSPQMYNGQMYVPECAKTHPVAQTE-------------------QH------ 271

  Fly   490 TFYPPVSVSEDDNSTSMRNSISALQQHCNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSM 554
                                 |:|.|...:||               .:|..|..|  |:|...:
 Frog   272 ---------------------SSLHQSQQMVT---------------QNYLPSQQD--GHLESDI 298

  Fly   555 NELSGNEYLPSANAYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYD-D 618
            ::              .:::.:|.|:...                           ||...|. |
 Frog   299 DK--------------TEFDQYLMYEPKS---------------------------DTELIYTID 322

  Fly   619 YEAEAYSNAMLP-----ATAASYY 637
            .::.|||..:||     |.:..||
 Frog   323 QDSGAYSTNLLPSLISEANSVCYY 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	51/70 (73%)
sox17b.2	NP_001090837.1	SOX-TCF_HMG-box	35..106	CDD:238684	51/70 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5873
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm47877
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040