Protein Alignment VGAT and SLC38A5

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: XP_005272751.2
• Gene: SLC38A5 / 92745
• HGNCID: 18070
• Length: 539
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 98/470 - (20%)
• Similarity: 183/470 - (38%)
• Gaps: 102/470 - (21%)

  Fly    94 EYRNEYQSTSFN-----EYDGRYQQTDGFRQGSIASEGSSFV----CEGEGGGGCKIDEFQAAWN 149
            |.|.|.|....|     :..|..|:.:||......:.||..|    .||:...|..:      :|
Human    45 ETRMELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSV------FN 103

  Fly   150 VTNAIQGMFIVSLPFAVLHGG-YWAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYV 213
            ::|||.|..|:.|.:|:.|.| .:.:..::.||.:..|:..:|:.|        ..:..:| :|.
Human   104 LSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTC--------AGIAGIR-AYE 159

  Fly   214 AIAKVCFGPKLGARAVSIAQLIEL----LMTCILYVVVCG-DLLAGTY----PQGSFDSRSWMLF 269
            .:.:..|||   |..|.:|.:|.|    .|:..|:::... .|:.||:    |:|.:..:..:|.
Human   160 QLGQRAFGP---AGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLI 221

  Fly   270 V---GIFLLPMGFLKSLKMV---STLSFWCTMSHIVINAVILGYCLLQIG--------------- 313
            :   .:.:||:..:|.|..:   |.||..|.:..:|  :||  |...|:|
Human   222 IIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLV--SVI--YKKFQLGCAIGHNETAMESEAL 282

  Fly   314 --------DWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSHIAA 370
                    :.......|::|.: ...::.::.|::.....:..:...:...||.......:....
Human   283 VGLPSQGLNSSCEAQMFTVDSQ-MSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIG 346

  Fly   371 AVF-----KAGFGYICFLTFQNDTQQVITNNLHSQGFKG----MVNFFLVIKALLSYPLPYYAAC 426
            |:|     .|.|||:.|.:      .|....||....|.    .|...:::...|:.|:..:...
Human   347 AMFCMYGLTATFGYLTFYS------SVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIR 405

  Fly   427 ELLERNFFRGPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTI--LMAIFIPHFSILMGFIGSFTG 489
            ..|::..|              .|:...|.....:.:|:..:  ::.|.:|....:.|.|||.:.
Human   406 RALQQLLF--------------PGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSA 456

  Fly   490 TMLSFIWPCYFHIKI 504
            ..|.||.|..|:::|
Human   457 PSLIFILPSIFYLRI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	83/411 (20%)
SLC38A5	XP_005272751.2	SLC5-6-like_sbd	93..484	CDD:294310	85/422 (20%)
		SdaC	93..476	CDD:223884	85/422 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158540
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840