DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VGAT and AT5G02170

DIOPT Version :9

Sequence 1:	NP_610938.1	Gene:	VGAT / 36574	FlyBaseID:	FBgn0033911	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_195837.2	Gene:	AT5G02170 / 831896	AraportID:	AT5G02170	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	457	Identity:	115/457 - (25%)
Similarity:	197/457 - (43%)	Gaps:	72/457 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 QGSIASEGSSFVCE------------GEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGGY 171
            |.|:.|...||:..            .:....|...  |:..|..|.:.|:.::::|:||..||:
plant   103 QSSVVSSIKSFLASHLQLSVPGDLLTPQENRSCTFS--QSVLNGINVLCGVALLTMPYAVKEGGW 165

  Fly   172 WAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIE 236
            ..:..:.....|..|||.:|.:|| |..|..       .:|..|.:..|| ..|...|||...:|
plant   166 LGLFILFSFGIITFYTGILLKRCL-ENSPGI-------HTYPDIGQAAFG-TTGRILVSILLYVE 221

  Fly   237 LLMTCILYVVVCGDLLAGTYPQGS-----FDSRSWMLF---VGIFLLPMGFLKSLKMVSTLSFWC 293
            |..:|:.|:::..|.|:..:|..|     |...|..:|   ..:.:||..:||.|.::|.||
plant   222 LYASCVEYIIMMSDNLSRMFPNTSLYINGFSLDSTQVFAITTTLIVLPTVWLKDLSLLSYLS--- 283

  Fly   294 TMSHIVINAVILGYCLLQIGD---WGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMID 355
              :..||::::|..||...|.   .|:.....::|:.|.|:::|:..|.:.|....|.:..:|.:
plant   284 --AGGVISSILLALCLFWAGSVDGVGFHISGQALDITNIPVAIGIYGFGFGSHSVFPNIYSSMKE 346

  Fly   356 RSKFNWMLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNL--HSQGFKGMVNFFLVIKALLSY 418
            .|||..:|..|.....:|........|..|.:..|...|.|:  |....|      :.:...:..
plant   347 PSKFPTVLLISFAFCTLFYIAVAVCGFTMFGDAIQSQFTLNMPPHFTSSK------IAVWTAVVT 405

  Fly   419 PLPYYAACELLERNFFRGPPKTKFPTIWNLDGEL------KVWGLG----FRVGVIVSTILMAIF 473
            |:..||.              |..|.:.:|: ||      |:...|    ||..:::||:::|:.
plant   406 PMTKYAL--------------TITPVMLSLE-ELIPSSSRKMRSKGVSMLFRTILVLSTLVVALT 455

  Fly   474 IPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDSGNA 538
            :|.|:.:...||||...:::.|:||..:|.|....|...:|....||:.:|::.|..|.|.:...
plant   456 VPFFATVAALIGSFIAMLIALIFPCLCYISIMKGRLTNFQIGICILIVIIGIVSGCCGTYSAIAR 520

  Fly   539 LI 540
            ||
plant   521 LI 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	106/411 (26%)
AT5G02170	NP_195837.2	SLC5-6-like_sbd	136..495	CDD:320982	100/395 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	129	1.000	Domainoid score	I1712
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1814
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570025at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2748
orthoMCL	1	0.900	-	-		OOG6_100570
Panther	1	1.100	-	-	O	PTHR48017
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.830