Protein Alignment VGAT and SLC38A1

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001265319.1
• Gene: SLC38A1 / 81539
• HGNCID: 13447
• Length: 503
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 108/464 - (23%)
• Similarity: 185/464 - (39%)
• Gaps: 91/464 - (19%)

  Fly    98 EYQSTSFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGC--------KIDEF--------QA 146
            |.|:.:..|.|.....::.|.:.......|.|:.:.|.....        |.||:        .:
Human    12 ELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMS 76

  Fly   147 AWNVTNAIQGMFIVSLPFAVLHGGYWA-IVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRD 210
            .:|::|||.|..|:.|.||:.:.|... :|.:..:..:..|:..:|:.|..|    ||.||
Human    77 VFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKE----TGCMV---- 133

  Fly   211 SYVAIAKVCFGPKLGARAVSIAQLIELLMTCILYV-VVCGDL------LAG---TYPQGSFDSRS 265
             |..:.:..|| ..|...:..|..::.....:.|: :|..:|      |.|   |:.....|.|.
Human   134 -YEKLGEQVFG-TTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRV 196

  Fly   266 WMLFV--GIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYCLLQI---------------- 312
            .::.|  || :||:..||:|..:...|.: ::|.:|...:::.|...||
Human   197 LVVIVTFGI-ILPLCLLKNLGYLGYTSGF-SLSCMVFFLIVVIYKKFQIPCIVPELNSTISANST 259

  Fly   313 -GDWGWSK-VRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRS--KFNWMLDWSHIAAAV- 372
             .|....| |.|:   .....:|..|.|::.....:..:...:.|||  |...:.:.|..|..|
Human   260 NADTCTPKYVTFN---SKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVM 321

  Fly   373 --FKAGFGYICFLTFQNDTQQVITNNLHSQGFKG-----MVNFFLVIKALLSYPLPYYAACELLE 430
              ..|.|||   |||.::.|   ::.||....|.     .|...:::..:|:.|:.::.    :.
Human   322 YFLTAIFGY---LTFYDNVQ---SDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFT----VR 376

  Fly   431 RNFFRGPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFI 495
            .:.|....||||    ||.....|..:     ::|...|:.||||....:.|.:|..:..||.||
Human   377 SSLFELAKKTKF----NLCRHTVVTCI-----LLVVINLLVIFIPSMKDIFGVVGVTSANMLIFI 432

  Fly   496 WPCYFHIKI 504
            .|...::||
Human   433 LPSSLYLKI 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	97/410 (24%)
SLC38A1	NP_001265319.1	SLC5-6-like_sbd	69..480	CDD:382020	97/407 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740