Protein Alignment VGAT and Slc38a4

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001344987.1
• Gene: Slc38a4 / 69354
• MGIID: 1916604
• Length: 547
• Species: Mus musculus
• Alignment Length: 607
• Identity: 117/607 - (19%)
• Similarity: 208/607 - (34%)
• Gaps: 222/607 - (36%)

  Fly    61 GMDGGDTTEMSS---NPFRNAGSWTNDGEGGGDGDGEYRNEYQ--STSFNEYDGRYQQTDGFRQG 120
            ||:..|...|:|   |....:..:..:|..|.....:|.:|:.  .|||.
Mouse    29 GMENSDKDAMNSQFANEDAESQKFLTNGFLGKKKLADYADEHHPGMTSFG--------------- 78

  Fly   121 SIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGG-YWAIVAMVGIAHIC 184
                                    .:::|::|||.|..|:.|.:|:.:.| ...|:.::.:|.:.
Mouse    79 ------------------------MSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLTVAILS 119

  Fly   185 CYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFG--PKLGARAVSIAQLIELLMTCILYVVV 247
            .|:..:|::...|    .|.::     |..:.:..||  .|:|| .:||.......|:..|:::.
Mouse   120 LYSVHLLLKTAKE----GGSLI-----YEKLGEKAFGWPGKIGA-FISITMQNIGAMSSYLFIIK 174

  Fly   248 ----------------CGD-LLAGTYPQGSFDSRSWMLFVGI-FLLPMGFLKSLKMVSTLSFWCT 294
                            .|: .|.|.|         .:|||.: .:||:..||:|..:...|.:..
Mouse   175 YELPEVIRAFMGLEENTGEWYLNGNY---------LVLFVSVGIILPLSLLKNLGYLGYTSGFSL 230

  Fly   295 MSHIVINAVILGYCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKF 359
            ...:...:|::           :.|.:....:.....:.|.:.|:.|..|.:.:|. |..:.|..
Mouse   231 SCMVFFVSVVI-----------YKKFQIPCPLPALDHNNGNLTFNNTLPIHMISLP-NDSESSGV 283

  Fly   360 NWMLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHSQGF--------KGMVNFFLVIKALL 416
            |:|:|::|...|..              |.:|| ...|||.|.        |....:| |..:..
Mouse   284 NFMMDYAHHNPAGL--------------DEKQV-AGPLHSNGVEYEAQGAEKCQPKYF-VFNSRT 332

  Fly   417 SYPLPYYA---AC---------ELLERNFFRGPPKTKFPTIWNLD--------------GELKVW 455
            :|.:|..|   .|         ||.:|:      :.|..|:.|:.              |.|..:
Mouse   333 AYAIPILAFAFVCHPEVLPIYSELKDRS------RRKMQTVSNISISGMLVMYLLAALFGYLSFY 391

  Fly   456 G--------------------LGFRVGVIVSTIL------------------------------- 469
            |                    |..|:.|:|:..|
Mouse   392 GDVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPRKPFSWLKHFGI 456

  Fly   470 ----------MAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKI--KGHLLDQKEI-AKDYLII 521
                      :.|.:|....:.||||:.:.|||.||.|..|::|:  |..|...::| |..:|:.
Mouse   457 AAIIIALNNILVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRSPQKIGALVFLVT 521

  Fly   522 GLGVLFGVIG------IYDSGN 537
            |:..:.|.:.      ||:..|
Mouse   522 GIIFMMGSMALIILDWIYNPPN 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	101/513 (20%)
Slc38a4	NP_001344987.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		2/4 (50%)
		SLC5-6-like_sbd	75..535	CDD:382020	104/551 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900