Protein Alignment VGAT and Slc38a2

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_780330.2
• Gene: Slc38a2 / 67760
• MGIID: 1915010
• Length: 504
• Species: Mus musculus
• Alignment Length: 537
• Identity: 110/537 - (20%)
• Similarity: 189/537 - (35%)
• Gaps: 160/537 - (29%)

  Fly    94 EYRNEYQSTS-FNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEF--------QAAWN 149
            |..:.|.|.| ||......|.........:..|..:|:.|...|......:|        .:.:|
Mouse    15 EDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFN 79

  Fly   150 VTNAIQGMFIVSLPFAVLHGG---YWAIVAMVGI-----AHICCYTGKVLVQCLYE--------- 197
            ::|||.|..|:.|.:|:.:.|   :..::..|.|     .|:...|.......|||
Mouse    80 LSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGL 144

  Fly   198 ------PDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIELLMTC-----ILYVVVCGDL 251
                  ....|.|.:....||:.|.|           ..:..:|:.||..     :.|  :.||.
Mouse   145 AGKLAASGSITMQNIGAMSSYLFIVK-----------YELPLVIKALMNIEDTNGLWY--LNGDY 196

  Fly   252 LAGTYPQGSFDSRSWMLFVGIFLLPMGFLKSLKMV---STLSFWCTMSHIVI------------- 300
            |.             :|...:.:||:..|::|..:   |.||..|.:..:::
Mouse   197 LV-------------LLVSLVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVE 248

  Fly   301 -----NAVILG-----------------YCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTSQ 343
                 |..:.|                 .|          :.|:.|.......::.::.||:...
Mouse   249 AALVANETVNGTFTQAALALAFNSTADDAC----------RPRYFIFNSQTVYAVPILTFSFVCH 303

  Fly   344 -IFLPTLE-------GNMIDRSKFNWM-LDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHS 399
             ..||..|       ..|::.||.::. :...::.||:    |||   |||....:..:   ||:
Mouse   304 PAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAAL----FGY---LTFYGHVESEL---LHT 358

  Fly   400 QG-FKG------MVNFFLVIKALLSYPLPYY----AACELLERNFFRGPPKTKFPTIWNLDGELK 453
            .. ..|      :|...:::...|:.|:..:    :...||       .|..:|.  |.....:.
Mouse   359 YSEIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLL-------CPTKEFS--WLRHSIIT 414

  Fly   454 VWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKI--KGHLLDQKEI-A 515
            |..|.|       |.|:.||:|....:.||||:....||.||.|..|:||:  |..:...::| |
Mouse   415 VTILSF-------TNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGA 472

  Fly   516 KDYLIIGLGVLFGVIGI 532
            ..:|:.|:.|:.|.:|:
Mouse   473 LCFLLSGIVVMIGSMGL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	99/486 (20%)
Slc38a2	NP_780330.2	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..96		19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		2/7 (29%)
		SLC5-6-like_sbd	69..491	CDD:382020	98/483 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830