Protein Alignment VGAT and slc38a2

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001038569.1
• Gene: slc38a2 / 566537
• ZFINID: ZDB-GENE-030131-9659
• Length: 504
• Species: Danio rerio
• Alignment Length: 513
• Identity: 117/513 - (22%)
• Similarity: 193/513 - (37%)
• Gaps: 129/513 - (25%)

  Fly   101 STSFNEYDGRYQQ------TDGFRQGSIASEGSSFVCE--------------GEGGGGCKIDEFQ 145
            ||:.|||. .||.      .:|.:...:.:|..:|:.:              |....|..:
Zfish    21 STNSNEYT-NYQDHASKVPLNGIQYSDVEAESQNFLSDHHLGKKKYEAEYSPGSASFGMSV---- 80

  Fly   146 AAWNVTNAIQGMFIVSLPFAVLHGGY-WAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVR 209
              :|:.|||.|..|:.|.:|:.:.|. ..::.:|.:|....|:..:|::...|    .|.:|
Zfish    81 --FNLGNAIMGSGILGLSYAMANTGIAMFVILLVAVAIFSLYSVHLLLKTANE----GGSLV--- 136

  Fly   210 DSYVAIAKVCFG-PKLGARAVSIAQLIELLMTCILYVV------VCGDLLAGT----YPQGSFDS 263
              |..:....|| |...|.:.||.......|...||:|      |....|...    |..|.:
Zfish   137 --YEQLGYKAFGIPGKLAASCSITMQNFGAMASYLYIVKYELPIVIRAFLDSNDNAWYTNGDY-- 197

  Fly   264 RSWMLFVGI-FLLPMGFLKSLKMV---STLSFWCTMSHIVINAVILGYCLLQI------------ 312
              .:|.|.: .:||:..||:|..:   |..|..|    :|...:::.|...||
Zfish   198 --LVLIVTMSIILPLSLLKNLGYLGYTSGFSLLC----MVFFLIVVIYKKFQIPCPLPENFINIT 256

  Fly   313 ------------GDWGWSKVRFSIDMENFPISLGVIVFSYTSQ-IFLPTLEGNMIDRS--KFNWM 362
                        .|....|.::.|.......::.::.|::... ..||..| .:.|||  |...:
Zfish   257 VNVSQPPQTNNSTDEECCKPKYFIFNSQTVYAVPILTFAFVCHPAILPMYE-ELKDRSRRKMQNV 320

  Fly   363 LDWSHIAAAV---FKAGFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYA 424
            .:.|.:...:   ..|.|||:.|      .:.|....||:  :..:.||.:|   ||...|....
Zfish   321 ANVSFLGMFIMYLLAALFGYLTF------NEAVEPELLHT--YSKVYNFDVV---LLIVRLAVLT 374

  Fly   425 ACELLERNFFRGPPKTKFP---TIWNLDGELKVWG----LGFRVGVIVSTILMAIFIPHFSILMG 482
            |..|.       .|...||   ::.:|.|..|.:.    :...|.::|...::.||:|....:.|
Zfish   375 AVTLT-------VPVVLFPIRTSVNHLLGASKEFSWPRHICITVALLVCVNILVIFVPTIRDIFG 432

  Fly   483 FIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKD--------YLIIGLGVLFGVIGI 532
            |||:....||.||.|..|:||     |.:||..|.        :||:|..|:.|.:.:
Zfish   433 FIGASAAAMLIFILPSAFYIK-----LVKKESMKSVQKIGATLFLIMGFLVMTGSMAL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	105/450 (23%)
slc38a2	NP_001038569.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..99		19/84 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		4/6 (67%)
		SLC5-6-like_sbd	72..488	CDD:444915	107/461 (23%)