Protein Alignment VGAT and slc38a2

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001011056.1
• Gene: slc38a2 / 496466
• XenbaseID: XB-GENE-6258676
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 108/517 - (20%)
• Similarity: 196/517 - (37%)
• Gaps: 126/517 - (24%)

  Fly    84 DGEGGGDGDGEYRNEYQSTSF---NEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEF- 144
            |.:.....|....:|||..:.   :.||...:......:.:::.:    .||.|...|  ...|
 Frog    12 DEDSSNSNDDLNYSEYQPKNHPIKSHYDMDIENVHFLLEPTMSKK----KCETEYLPG--TTSFG 70

  Fly   145 QAAWNVTNAIQGMFIVSLPFAVLHGGY-WAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRV 208
            .:.:|::|||.|..|:.|.:|:.:.|. ..::.:|.:.....|:..:|::...|    .|.::
 Frog    71 MSVFNLSNAIVGSGILGLSYAMANTGIALFMILLVFVTVFSLYSIHLLLKTANE----GGSLL-- 129

  Fly   209 RDSYVAIAKVCFG--PKLGARAVSIAQLIELLMTCILYVV----------------------VCG 249
               |..:....||  .||.|......|.|. .|:..||:|                      :.|
 Frog   130 ---YEQLGLKAFGIPGKLAASGSVTLQNIG-AMSSYLYIVKYELPLVIKALMDIKESNGEWYLNG 190

  Fly   250 DLLAGTYPQGSFDSRSWMLFVGI-FLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGY------ 307
            |.|              ::.|.: .:||:..|::|..:...|.:..:..:....|:: |
 Frog   191 DYL--------------VIMVSLAIILPLSLLRNLGYLGYTSGFSPLCMVFFLIVVI-YKKFEIP 240

  Fly   308 CLLQI-----------------GDWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMID 355
            |.|:.                 .|....|.::.:.......::.::.||:.....:..:...:..
 Frog   241 CPLEAMNMTSNSSSHDHMAHNETDDEMCKPKYFVFNSQTVYAVPILTFSFVCHPAVLPIYQELKG 305

  Fly   356 RSKFNWMLDWSHIA-AAVF-----KAGFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLV-IK 413
            ||: ..|::.|::: .|:|     .|.|||   |||.:..:..:.:. :|:.|...|.|.:| :.
 Frog   306 RSR-RRMMNVSNVSFFAMFIMYLLAALFGY---LTFYSKVEPELLHT-YSKVFGAGVIFVVVRLA 365

  Fly   414 ALLSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELKVWGLGF--------RVGVIVSTILM 470
            .|::..|..               |...||...:|: ||...|..|        ...::..|.::
 Frog   366 VLMAVTLTV---------------PIVIFPIRSSLN-ELFCSGKDFAWIRHILITFLILAFTNVL 414

  Fly   471 AIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGI 532
            .||:|....:.||||:....||.||.|..|:|:     |.:||..|....|| .:||.:.||
 Frog   415 VIFVPTIRDIFGFIGASAAAMLVFILPSAFYIR-----LVKKESMKSVQKIG-ALLFLIGGI 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	97/454 (21%)
slc38a2	NP_001011056.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..92		19/85 (22%)
		SLC5-6-like_sbd	65..482	CDD:444915	98/460 (21%)