Protein Alignment VGAT and slc32a1

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001004943.1
• Gene: slc32a1 / 448348
• XenbaseID: XB-GENE-489830
• Length: 518
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 219/502 - (43%)
• Similarity: 300/502 - (59%)
• Gaps: 42/502 - (8%)

  Fly    49 HSQQAQHKAMEAGMDGGDTTEMSSNPFRNAGSWTNDGEGGGDGDGEYRNEYQSTSFNEYDGRYQQ 113
            |.|..|...::..:..||.|                    .:||..|                 |
 Frog    54 HRQGLQMDILKTEVPSGDPT--------------------AEGDSHY-----------------Q 81

  Fly   114 TDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGGYWAIVAMV 178
            .||....|.||:......|....|..||..::|.|||||||||||::.||:|:|||||..:..::
 Frog    82 RDGTGPPSSASKDEGLCSELSSYGKPKITAWEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLII 146

  Fly   179 GIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFG---PKLGARAVSIAQLIELLMT 240
            ..|.:||||||:|:.|||| :...|:.||||||||.||..|..   ||||.|.|::||:|||:||
 Frog   147 FAAVVCCYTGKILIACLYE-ENEDGETVRVRDSYVDIANACCAPRFPKLGGRVVNVAQIIELVMT 210

  Fly   241 CILYVVVCGDLLAGTYPQGSFDSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVIL 305
            |||||||.|:|:..::|......:||.:.....|||..|||:||.||..|..||::|.|||.:::
 Frog   211 CILYVVVSGNLMYNSFPSLPISQKSWSIIATAMLLPCAFLKNLKAVSKFSLLCTLAHFVINVLVI 275

  Fly   306 GYCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSHIAA 370
            .|||.:..||.|.||:|.||::.||||:|:||||||||||||:|||||....:|:.|::|:||||
 Frog   276 AYCLSRARDWAWDKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQSPKEFHCMMNWTHIAA 340

  Fly   371 AVFKAGFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFR 435
            .:.|..|..:.:||:.::|::|||:||.|. .:.:||.|||.|||||||||::||.|:||::.|:
 Frog   341 CILKGLFALVAYLTWADETKEVITDNLPST-IRAVVNLFLVAKALLSYPLPFFAAVEVLEKSLFQ 404

  Fly   436 GPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCYF 500
            ...:..||..:..||.||.|||..|..::|.|:||||::|||::|||..||.||..|.|:.|..|
 Frog   405 EGARAFFPNCYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLF 469

  Fly   501 HIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDSGNALINAFEIGL 547
            |:|:....|...::..|..|..:|.:..|.|...|...||.||...:
 Frog   470 HLKLLWRKLQWHQVFFDVSIFVIGSICSVSGFVHSLEGLIEAFRFNI 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	195/391 (50%)
slc32a1	NP_001004943.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..98		12/68 (18%)
		Aa_trans	108..505	CDD:279788	197/398 (49%)