Protein Alignment VGAT and Slc36a4

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001101597.1
• Gene: Slc36a4 / 315439
• RGDID: 1311528
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 111/515 - (21%)
• Similarity: 187/515 - (36%)
• Gaps: 159/515 - (30%)

  Fly    92 DGEYRNEYQSTSFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQG 156
            ||....|.:.|.....  ::.|.||       ..|.|||              |...::.....|
  Rat    30 DGSSDEEQEQTLLPMQ--KHYQLDG-------QHGISFV--------------QTLMHLLKGNIG 71

  Fly   157 MFIVSLPFAVLHGGYWAIV------AMVGIAHICCYTGKVLVQCLY------------------- 196
            ..::.||.|:.:.|   ||      ..:||..:.|.  .:||:|.:
  Rat    72 TGLLGLPLAIKNAG---IVLGPISLVFIGIISVHCM--HILVRCSHFLCQRFKKSTLGYSDTVSF 131

  Fly   197 --EPDP--------ATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIE--------LLMTCIL 243
              |..|        |.|:  .|.|.::.|.      :||..:|.|..|.|        ||.|.:
  Rat   132 AMEASPWSCLQRQAAWGR--SVVDFFLVIT------QLGFCSVYIVFLAENVKQVHEGLLETTV- 187

  Fly   244 YVVVCGDLLAGTYPQGSFDSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYC 308
             ||.....|:....:.|.|.|.:||.....|:.:.|::.||.:..|||...:|......:|..|.
  Rat   188 -VVSNSSDLSQVCERRSVDLRVYMLCFLPLLILLVFIRELKSLFVLSFLANISMAASLVIIYQYV 251

  Fly   309 LLQIGD-------WGWSKVRFSIDMENFPISLGVIVFSYTS-QIFLPTLEGNMIDRSKFNWMLDW 365
            :..:.|       .||.|         :|:..|..||::.. .:.|| ||..|.:..:|...|
  Rat   252 VRSMPDPHNLPIVAGWKK---------YPLFFGTAVFAFEGIGVVLP-LENQMRESKRFPQAL-- 304

  Fly   366 SHIAAAVFK------AGFGYICFLTFQNDTQQVITNNLHS-----QGFKGMVNFFLVIKALLSYP 419
             :|..|:..      |..||:|   |:::.:..||.||..     |..|.:.:|.:.:    :|.
  Rat   305 -NIGMAIVTVLYISLATLGYMC---FRDEIKGSITLNLPQDMWLYQSVKILYSFGIFV----TYS 361

  Fly   420 LPYYAACELLERNFFRGPPKTKFPTI-------WNLDGELKVWGLGFRVGVIVSTILMAIFIPHF 477
            :.:|...|::            .|.:       |..     :...|.|..::..|...|:.||..
  Rat   362 IQFYVPAEII------------IPAVTARLHAKWKC-----ICDFGIRSLLVSITCAGAVLIPRL 409

  Fly   478 SILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDY-----LIIGLGVLF-GVIG 531
            .|::.|:|:.:.:.|:.|.|         .|::....:||:     ::..:.:.| |.:|
  Rat   410 DIVISFVGAVSSSTLALILP---------PLVEILTFSKDHYNVWMVLKNISIAFTGFVG 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	100/463 (22%)
Slc36a4	NP_001101597.1	SLC5-6-like_sbd	54..469	CDD:444915	104/482 (22%)