Protein Alignment VGAT and Slc36a3

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001019935.1
• Gene: Slc36a3 / 303148
• RGDID: 1309092
• Length: 477
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 106/492 - (21%)
• Similarity: 183/492 - (37%)
• Gaps: 108/492 - (21%)

  Fly   108 DGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMFI------------- 159
            |||.|: :.|.....:|:|||     .......:...:......:|:  |||
  Rat    10 DGRCQR-NTFGGSKASSKGSS-----SSSSNNTVSSKKKPRRKADAL--MFIQIFIHLLKSNIGT 66

  Fly   160 --VSLPFAVLHGGYW-AIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAI------ 215
              :.||.||.:.|.. ..|:::.|..:..:...:|:.|      |.....|::.|:|..
  Rat    67 GFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNC------ACHLTSRLQRSFVNYEETTMY 125

  Fly   216 -AKVCFGPKL------GARAVSIAQLIELLMTCILYVVVCGDLLAGTYPQGSF------------ 261
             .:.|..|.|      |...||...::..|..|.:|.:...|.|.....:..|
  Rat   126 SLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQSLV 190

  Fly   262 -----DSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYCLLQIGDWGWSKVR 321
                 |:|.:||.:..||:.:..:::.:::|..|...|::.:...|:|..| |:||..  .|.:.
  Rat   191 MTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEY-LIQIPH--HSHLP 252

  Fly   322 FSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSHIAAAVFKAG-----FGYIC 381
            .....:.|.:..|..:|::.....:..|:..|....:|          .||...|     |.|||
  Rat   253 LVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQF----------PAVLYLGMSFVIFLYIC 307

  Fly   382 -----FLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPPKTK 441
                 ::.|..|||..||.||.:......|.....:....:|.|.::...|::
  Rat   308 LGTLGYMKFGADTQASITLNLPNCWLYQSVKLMYSVGIFFTYALQFHVPAEII------------ 360

  Fly   442 FPTI-------WNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCY 499
            .|.:       |.|..:|.|     |..::..|...|:.||...:::..:||.:.:.|:.|.|..
  Rat   361 VPYVVSRASENWALFIDLTV-----RAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPL 420

  Fly   500 FHI-KIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDS 535
            ..| ......:....||||.:|..||:|..|:|.|.:
  Rat   421 LEIATFYSENISCTTIAKDIMISILGLLGCVLGTYQA 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	96/452 (21%)
Slc36a3	NP_001019935.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		9/37 (24%)
		SLC5-6-like_sbd	52..458	CDD:444915	95/442 (21%)