DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VGAT and Slc38a7

DIOPT Version :9

Sequence 1:	NP_610938.1	Gene:	VGAT / 36574	FlyBaseID:	FBgn0033911	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	NP_001003705.1	Gene:	Slc38a7 / 291840	RGDID:	1303268	Length:	463	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	100/469 - (21%)
Similarity:	173/469 - (36%)	Gaps:	98/469 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 EGEGGGG----CKIDEFQAAWNVTNAIQGMFIVSLPFAV-LHGGYWAIVAM-VGIAHICCYTGKV 190
            |||...|    .......|.:.|.||..|..:::.|.|. ..||..|.:|: :|:.........:
  Rat    38 EGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVI 102

  Fly   191 LVQCLYEPDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIELLMTCILYVVVCGD----- 250
            |..|....:..|.|.|        :..||  .||......||..:....|||.::::.||
  Rat   103 LAYCSQASNERTYQEV--------VWAVC--GKLTGVLCEIAIAVYTFGTCIAFLIIIGDQQDKI 157

  Fly   251 -LLAGTYPQGSFDSRSW--------MLFVGIFLLPM------GFLKSLKMVSTLSFWCTMSHIVI 300
             .:....|.|:..| .|        .|...:|:||:      ||.|....:|.:..|...:.::|
  Rat   158 IAVMAKEPDGASGS-PWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASSLSVVGTWYVTAIVII 221

  Fly   301 NAVILGYCLLQIGDWGWSKVRFSIDMENFPIS-------LGVIVFSYTSQIFLPTLEGNMIDRSK 358
            ..:           |...::|.. |:...|.|       :..|.|.:...:....:..:|.....
  Rat   222 KYI-----------WPDKEMRPG-DILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPQV 274

  Fly   359 FNW-------MLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHSQGFK-GMVNFFLVIKAL 415
            ..|       |:    ||.||: .|.|...||||.......:..:..|:... .:...|:::..|
  Rat   275 KTWGGVVTAAMV----IALAVY-MGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVL 334

  Fly   416 LSYPLPYYAACELLERNF--FRGPP----------KTKFPTIWNLDGELKVWGLGFRVGVIVSTI 468
            .|||:.::....::|..:  ::|.|          :....|:        ||        .:.|:
  Rat   335 TSYPILHFCGRAVVEGLWLRYKGTPVEEDVGRERRRRVLQTL--------VW--------FLLTL 383

  Fly   469 LMAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIY 533
            |:|:|||....::..||......: ||:|....|:.|...:::.:.|..:.::..|||...:|.:
  Rat   384 LLALFIPDIGKVISVIGGLAACFI-FIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAF 447

  Fly   534 DSGNALINAFEIGL 547
            ..|....||..:.|
  Rat   448 IFGQTTANAVFVDL 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	92/437 (21%)
Slc38a7	NP_001003705.1	SLC5-6-like_sbd	49..458	CDD:382020	95/453 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740