Protein Alignment VGAT and slc-36.1

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_499743.2
• Gene: slc-36.1 / 259544
• WormBaseID: WBGene00012804
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 118/511 - (23%)
• Similarity: 199/511 - (38%)
• Gaps: 91/511 - (17%)

  Fly    72 SNPFRNAGSWTNDGEGGGDGDGEYRNEYQSTSFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGG 136
            :||.|: |....|.|....||.|.:...::|        ..:.....|..:.:|.|
 Worm     2 ANPARD-GYQEFDNEPEAPGDTEVQTPRRNT--------VSEDTSLFQDRLPTENS--------- 48

  Fly   137 GGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGG-YWAIVAMVGIAHICCYTGKVLVQCLYEPDP 200
                :...||..::..|:.|..::|||.|..|.| :..::..|.|..||.|..:.:|...:....
 Worm    49 ----LTPEQAFIHMVKAMLGTGLLSLPLAFKHSGLFLGLILTVLICLICLYCMRQVVFAAHFVCN 109

  Fly   201 ATGQMVRVRD--SYVAIAK--VCFGPKLGAR-------AVSIAQLIELLMTCILYVVVCGDLLAG 254
            ..|     ||  .|..|.:  |..||....|       .|::...|..|..|.:|.|...|.|..
 Worm   110 RNG-----RDLIDYANIMRGAVEMGPPWIKRNGYFFKQLVNVNMFISQLGFCCVYFVFMADNLED 169

  Fly   255 TYPQGS---FDSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYCLLQ---IG 313
            .:...:   .....|||.:.|.:|.:..::.|.:::..:....:.::|..||:|.:.|..   |.
 Worm   170 FFNNNTSIHLSKAVWMLLLLIPMLSICSIRRLSILAPFAMAANVVYVVAVAVVLFFFLSDLRPIS 234

  Fly   314 DWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKF---NWMLDWSHIAAAVFKA 375
            ...|    |. ...:.|:..|.::|::.....:..:|..|.....|   |.:|:.|.:......:
 Worm   235 SLPW----FG-KATDLPLFFGTVMFAFEGVAVIMPIENRMQSPHAFISWNGVLNSSCLVVLAIFS 294

  Fly   376 GFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPP-- 438
            ..|:..:|:..||.:...|.||....|...:....|...::||||.:|...|.:|:...|..|
 Worm   295 VTGFYGYLSLGNDVKDTATLNLPMTPFYQTIKLMFVACIMISYPLQFYVPMERIEKWITRKIPVD 359

  Fly   439 -KTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIW-PCYFH 501
             :|.:..|....|             ::.|..:|..|||.::.:..||:|:|..::.:: ||.
 Worm   360 KQTLYIYIARYSG-------------VILTCAIAELIPHLALFISLIGAFSGASMALLFPPCI-- 409

  Fly   502 IKIKGHLLDQKEIAKDYLIIGLGV------LFGVIGIYDSG--NALINAFEIGLPF 549
                 .||  ...||:.|..||.:      .|..|| :.:|  :|||   ||...|
 Worm   410 -----ELL--TSYAKNELSTGLWIKNIVLLTFAFIG-FTTGTYSALI---EIAKTF 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	98/419 (23%)
slc-36.1	NP_499743.2	SLC5-6-like_sbd	50..445	CDD:444915	99/427 (23%)