Protein Alignment VGAT and Slc36a1

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_694779.3
• Gene: Slc36a1 / 215335
• MGIID: 2445299
• Length: 475
• Species: Mus musculus
• Alignment Length: 511
• Identity: 114/511 - (22%)
• Similarity: 191/511 - (37%)
• Gaps: 102/511 - (19%)

  Fly    70 MSSNPFRNAGSWTNDGEGGGDGDGEYRNEYQSTSFNEYDGRYQQTDGFRQGSI--ASEGSSFVCE 132
            ||:...||                |..::|.||..:..:...:....|..||.  ..|.||...
Mouse     1 MSTQRLRN----------------EDYHDYSSTDVSPEESPSEGLGSFSPGSYQRLGENSSMTW- 48

  Fly   133 GEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLHGGYW---AIVAMVGIAHICCYTGKVLVQC 194
                       ||...::.....|..::.||.||.:.|..   ..:.::||..:.|.  .:||:|
Mouse    49 -----------FQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCM--GILVKC 100

  Fly   195 LY---------------------EPDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIAQLIELL 238
            .:                     |..|:|  .||....:            |.|.|....::..|
Mouse   101 AHHLCRRLNKPFLDYGDTVMYGLECSPST--WVRNHSHW------------GRRIVDFFLIVTQL 151

  Fly   239 MTCILYVVVCGD-------LLAGT----------YPQGSFDSRSWMLFVGIFLLPMGFLKSLKMV 286
            ..|.:|.|...|       ...||          .|..:.|||.:||....||:.:.|:::|:::
Mouse   152 GFCCVYFVFLADNFKQVIEAANGTTTNCNNNVTVIPTPTMDSRLYMLSFLPFLVLLSFIRNLRVL 216

  Fly   287 STLSFWCTMSHIVINAVILGYCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTS-QIFLPTLE 350
            |..|....:|..|...:|..:.:.:|.|  .|.:......:.:|:..|..:|::.. .:.|| ||
Mouse   217 SIFSLLANISMFVSLIMIYQFIVQRIPD--PSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLP-LE 278

  Fly   351 GNMIDRSKFNWMLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHSQGFKGMVNFFLVIKAL 415
            ..|.|..||..:|........|.....|.:.:|.|..:.:..||.||.:......|.....|...
Mouse   279 NKMKDSQKFPLILYLGMAIITVLYISLGSLGYLQFGANIKGSITLNLPNCWLYQSVKLLYSIGIF 343

  Fly   416 LSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSIL 480
            .:|.|.:|.|.|::.....     ::.|..:.|..:|.|     |..::..|.::||.||...::
Mouse   344 FTYALQFYVAAEIIIPAIV-----SRVPEHFELMVDLCV-----RTAMVCVTCVLAILIPRLDLV 398

  Fly   481 MGFIGSFTGTMLSFIWPCYFH-IKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDS 535
            :..:||.:.:.|:.|.|.... :...|..:....:.||.||..||.:..|:|.|:|
Mouse   399 ISLVGSVSSSALALIIPPLLEVVTYYGEGISPLTVTKDALISILGFVGFVVGTYES 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	98/431 (23%)
Slc36a1	NP_694779.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		8/46 (17%)
		SLC5-6-like_sbd	47..452	CDD:444915	98/445 (22%)