Protein Alignment VGAT and Slc38a5

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_766067.2
• Gene: Slc38a5 / 209837
• MGIID: 2148066
• Length: 479
• Species: Mus musculus
• Alignment Length: 504
• Identity: 106/504 - (21%)
• Similarity: 207/504 - (41%)
• Gaps: 127/504 - (25%)

  Fly   109 GRYQQTDGF----RQGSIASEGSSFV-CEGEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVLH 168
            |..|:.:||    |..:...:...|: .||:...|..:      :|::|||.|..|:.|.:|:.|
Mouse    27 GYRQEREGFLPTTRNPATGRKPVQFLDFEGKTSFGMSV------FNLSNAIMGSGILGLAYAMAH 85

  Fly   169 GG-YWAIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFGPKLGARAVSIA 232
            .| .:.:..::.||.:..|:..:|:.|        ..:|.:| :|..:.:..|||   |..|.:|
Mouse    86 TGVIFFLALLLCIALLSSYSIHLLLTC--------ASVVGIR-AYEQLGQRAFGP---AGKVVVA 138

  Fly   233 QLIEL----LMTCILYVVVCG-DLLAGTY----PQGSFDSRSWMLFVGI---FLLPMGFLKSLKM 285
            .:|.|    .|:..|:::... .|:.||:    |:|.:..:..:|.:.:   .:||:..:|.|..
Mouse   139 IIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGY 203

  Fly   286 V---STLSFWCTMSHIVINAVILGYCLLQIG--------------------DWGWSKVRFSIDME 327
            :   |:||..|.:..::  :||  |...|||                    :.......|::|.:
Mouse   204 LGYTSSLSLTCMLFFLI--SVI--YKKFQIGCDVSHNDTVVEAEQAPLQAFNSSCEAELFTVDSQ 264

  Fly   328 NFPISLGVIVFSYT---------SQIFLPTLEGNMIDRSKFNWMLDWSHIAAAVF-----KAGFG 378
             ...::.::.|::.         :::..||       :.:...:.:.|  ..|:|     .|.||
Mouse   265 -MSYTVPIMAFAFVCHPEVLPIYTELCRPT-------QRRMQAVANMS--IGAMFIMYGLTATFG 319

  Fly   379 YICFLTFQNDTQQVITNNLHSQGFKGM----VNFFLVIKALLSYPLPYYAACELLERNFFRGPPK 439
            |:.|.:    |.:.....:::|  :.|    |...:::...|:.|:..:.....|::..|   |.
Mouse   320 YLTFYS----TVKAEMLEMYTQ--EDMLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLF---PS 375

  Fly   440 TKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKI 504
            ..|.  |     |:...:...:.::|:  ::.|.:|....:.|||||.:...|.||.|..|:::|
Mouse   376 KAFS--W-----LRHVAIALILLILVN--ILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRI 431

  Fly   505 ----KGHLLDQKEIAKDYLIIGLGVLFGVIGIYDSGNALINAFEIGLPF 549
                ...|....:|.        .:.|||:|:      |..|..:|..|
Mouse   432 VPTEVEPLFSWPKIQ--------ALCFGVLGV------LFMAISLGFMF 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	93/446 (21%)
Slc38a5	NP_766067.2	SLC5-6-like_sbd	56..466	CDD:444915	98/473 (21%)