Protein Alignment VGAT and R02F2.8

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_498173.1
• Gene: R02F2.8 / 187530
• WormBaseID: WBGene00019837
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 99/533 - (18%)
• Similarity: 178/533 - (33%)
• Gaps: 165/533 - (30%)

  Fly   103 SFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMFIVSLPFAVL 167
            |..:.||....|:....|.|.  |:.|:. ||..||..| ....|......|.|:.::||  ..:
 Worm     8 STGDKDGPTSHTNEKGIGWII--GAIFII-GETAGGGMI-ALSYALTSMGLIPGLILLSL--CSI 66

  Fly   168 HGGYWAIVAMVGIAHICCYTGKVLV--------QCLYEPDPATGQMVRVRDSYVAIAKVCFGPKL 224
            ...|.|:.        .|:|.|::.        .|              |..|..:|....|.|:
 Worm    67 FSLYTALE--------LCWTWKIMQNRWPEYRDHC--------------RKPYGEMAYRTIGRKM 109

  Fly   225 GARAVSIAQLIELLMTCILYVVVCGDLLAGTYPQGSFDSRS--WMLFVGIFLLPMGFLKSLKMVS 287
            .:....:..:.::....:|.::...:|....:...|.|...  .:|.||:.:.|...|.     |
 Worm   110 RSFIAFMICITQIGFATVLVLLAAKNLSILLHFFFSLDINQCYLILIVGLAVWPATMLP-----S 169

  Fly   288 TLSFW------CTMSHIVINAVILGYCLLQIGDWGWSKVRFSIDMENFPI--------------- 331
            .:.||      ...|...:..|::|..                  .:.|:
 Worm   170 PMHFWQAALFSAGSSTCAVILVVVGLA------------------HDAPVCAQDAPHEEPNLLKA 216

  Fly   332 --SLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSH-IAAAVFKAGFGYIC-----FLTFQND 388
              :.|..||::.....|||::.:|...:.|      .| :..|:......|:|     :..:.:.
 Worm   217 FMAFGTFVFAFGGHATLPTIQHDMKKPAHF------VHSVVLAIIFCTMLYMCIAVGGYFVYGST 275

  Fly   389 TQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELK 453
            ..:.|..:|..:..:..||..:.:..:.:..:                   ...|.|..::..||
 Worm   276 VGEAIIPSLQIKWIQQTVNLMIAVHVITTIVI-------------------VMSPPIQQVEQLLK 321

  Fly   454 VWGLGFRVGV---IVSTIL------MAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLL 509
            |   ..:.||   :|.:||      :.:.||||..::..||:.|..:::.|.|..|::.|:...:
 Worm   322 V---PHKFGVKRFLVRSILFWFVIFIGLSIPHFGPVLDLIGASTMVLMTLILPPIFYLSIRTQEI 383

  Fly   510 -------------------DQKEIAK--DYLIIGLG---VLFGVIG----IYDSGNALINA---- 542
                               ..|||.:  ..||:.|.   ::||:||    ...|...|:.:
 Worm   384 IWLQGNEKSDAAEPTHERATFKEILRLTPKLILALNAAVLIFGIIGGTLSTVTSVIRLVGSDMAA 448

  Fly   543 ------FEIGLPF 549
                  |..||||
 Worm   449 PCYYQYFTKGLPF 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	79/464 (17%)
R02F2.8	NP_498173.1	Aa_trans	22..416	CDD:279788	82/472 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52048
OrthoDB	1	1.010	-	-		D570025at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100570
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.730