Protein Alignment VGAT and F21D12.3

DIOPT Version :9

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_495532.2
• Gene: F21D12.3 / 174201
• WormBaseID: WBGene00017663
• Length: 496
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 99/478 - (20%)
• Similarity: 171/478 - (35%)
• Gaps: 135/478 - (28%)

  Fly   137 GGCKIDEFQAAWNVTNAIQGMFIVSLPFAV-LHGGYWAIVAMVGIAHICCYTGKVLVQC---LYE 197
            |..||....||..:...:.|..:|::|.|. |.|....|:.|:.:|....|||.:|.:.   :.|
 Worm    40 GKHKIGWVIAAIFIIADMVGGGVVAMPVAFKLSGLPMGILIMLTVAVSFEYTGYLLGKVWNKIME 104

  Fly   198 PDPATGQMVRVRDSYVAIAKVCFGPKL-------------GARAVSI---AQLIELLMTCILYVV 246
            .:|..|.   .|..:..:||...|..:             |...|.:   |.:|...::.:|:|
 Worm   105 RNPHIGV---CRKPFPEMAKRTMGTNMQRFTSVLGNVTQFGVSVVYLLLSANIIHFFISHVLHV- 165

  Fly   247 VCGDLLAGTYPQGSFDSRSWMLFVGI--FLL-PMGFLKSLKMVSTLSFWCTMSHIVINAVI---- 304
                           ||.|..|.:.:  ||: |...|     .|...||..:...::..||
 Worm   166 ---------------DSISNCLVITVLAFLIWPFTLL-----ASPGEFWVVIVFAMLTTVIAVVS 210

  Fly   305 --LGYCLLQIGDWGWSKVRFSIDMENFPI-SLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWS 366
              .|..|....  .:|.|.:.:......| |.|:.:|:::.....||::.:|.:...|
 Worm   211 IHTGIALDSTA--CFSAVSYPVTTSTSTILSFGIFLFAFSGHYVFPTIQHDMKNPRDF------- 266

  Fly   367 HIAAAVFKAGFGYI------CFLTF---------------QNDTQQVITNNLHSQGFKGMVNFFL 410
              ..::|....|.:      |...|               |:.:.|::.|.:.|  |..::...:
 Worm   267 --TKSIFAGFLGVVILYLPLCIFAFVVYGDSMTDSVIYSIQSPSLQLLANLMIS--FHCIMTLVI 327

  Fly   411 VIKALLSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELKVWGLG---FRVGVIVSTILMAI 472
            ||.. |:..:.:||...                         ..:|:|   .|..|:...:.:|:
 Worm   328 VINP-LNQEVEHYAKIS-------------------------HAFGIGRVITRTIVLFLVLFVAL 366

  Fly   473 FIPHFSILMGFIGSFTGTMLSFIWPCYFHIKI---------KGHLLDQKEIA----KDYLIIGLG 524
            .:|.|..:|..:|:.|..|...:.|..|::..         ||.:...:|:.    |..|||.|.
 Worm   367 TVPDFQPVMNLVGASTIPMGCAVLPSLFYLYSEAATEEEWRKGKIPTLREVLDRTDKTVLIINLI 431

  Fly   525 VLF-----GVIGIYDSGNALINA 542
            ::|     ||:|.|.....||.|
 Worm   432 IIFGAILGGVLGSYQGVLKLIKA 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:382020	92/460 (20%)
F21D12.3	NP_495532.2	SLC5-6-like_sbd	42..442	CDD:382020	92/462 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52048
OrthoDB	1	1.010	-	-		D570025at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100570
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.730