Protein Alignment VGAT and slc-36.2

DIOPT Version :10

• Sequence 1: NP_610938.1
• Gene: VGAT / 36574
• FlyBaseID: FBgn0033911
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001040812.1
• Gene: slc-36.2 / 173442
• WormBaseID: WBGene00020837
• Length: 449
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 113/497 - (22%)
• Similarity: 191/497 - (38%)
• Gaps: 106/497 - (21%)

  Fly    97 NEYQSTSFNE---YDGRYQQTDGFRQGSIASEGSSFVCEGEGGGGCKIDEFQAAWNVTNAIQGMF 158
            :.|.:...||   ..|.:|.|.|....|...:..|...:            ||..::...:.|..
 Worm     4 SSYDTARGNELLPLRGSHQPTMGEMFASRVRDSRSITAD------------QALIHMIKVMMGTG 56

  Fly   159 IVSLPFAVLHGGYW-AIVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAK----- 217
            ::|||.|..|.|.| .::.:..|..||.|..:.|:         .||      .|:...|
 Worm    57 MLSLPLAFKHSGIWLGLILLCFICLICIYCTRQLI---------FGQ------HYITFIKREQRM 106

  Fly   218 ---------VCFGPK-------LGARAVSIAQLIELLMTCILYVVVCGDLLAGTYPQGSFDSRSW 266
                     |..||.       |..:.|:|...:.....|.:|.|...|.|...:.|.|....|.
 Worm   107 DYANVMRSAVELGPAWIRGHGYLFKQMVNINMFVAQFGFCCVYFVFMADNLKQFFDQTSSIHISQ 171

  Fly   267 MLFVGIFLLPMGFL---KSLKMVSTLSFWCTMSHIVINAVILGYCLLQIGDWGWSKVRFSID--- 325
            ..::.:.|:|:..|   :.||.::.|:......:|:...::|...   ..||.      .:|
 Worm   172 AGWIALLLIPISALCTIRELKALAPLAAVANFVYIIAVVIVLADL---FSDWQ------PLDSLP 227

  Fly   326 ----MENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKF---NWMLDWSHIAAAVFKAGFGYICFL 383
                :||.|:..|.::|::.....:..:|..|.:...|   |.:|:.|.|...:.....|:..||
 Worm   228 AFGAVENLPLFFGTVMFAFEGVAVVLPIENQMNEPIHFITPNGVLNTSCILVLLVYMTVGFFGFL 292

  Fly   384 TFQNDTQQVITNNLHSQGFKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPPKTK-FPTIWN 447
            .:.||.:..:|.||....|...:....|:..|:||||.:|...|.:|:...|...:.| .|.|:
 Worm   293 RYGNDIKDTLTLNLPQTPFYQAIKVMFVLCILVSYPLQFYVPMERVEKWIKRKVVEAKQEPMIY- 356

  Fly   448 LDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWP------CYFHIKIKG 506
                      ..|.|.::.|..||..|||.::.:..:||..||.|:.::|      |.:
 Worm   357 ----------AIRFGGVLLTCAMAQLIPHLALFISLVGSVAGTSLTLVFPPLIELLCSY------ 405

  Fly   507 HLLDQKEIAKDYLIIGLGVL-FGVIGI----YDSGNALINAF 543
               .::|:.|...|..:|:: |.::|.    |.|...:|.||
 Worm   406 ---SKQELTKWVWIRNIGLMAFAMVGFTTGTYASMVQIIEAF 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VGAT	NP_610938.1	SLC5-6-like_sbd	144..533	CDD:444915	99/435 (23%)
slc-36.2	NP_001040812.1	SLC5-6-like_sbd	37..441	CDD:444915	102/459 (22%)