DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cg and CRZ1

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_014371.1	Gene:	CRZ1 / 855704	SGDID:	S000004972	Length:	678	Species:	Saccharomyces cerevisiae

Alignment Length:	184	Identity:	52/184 - (28%)
Similarity:	77/184 - (41%)	Gaps:	37/184 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 QKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERP--YSCDECGKSF 301
            |||....:||.::.        :.||..:.....|::.     ...|..::.|  ::||.|||.|
Yeast   527 QKVGFKNDDNHENN--------DNGTFSVKKNDNLEKL-----DSVTNNRKNPANFACDVCGKKF 578

  Fly   302 LLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTH 366
            ...::|.:|.|.||.|||.||:.|||:||.:|....|..||:.::.|.|....|.
Yeast   579 TRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKD---------- 633

  Fly   367 SRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGER---PYVCEECGESFAQEN 417
                  .:|:   .||:.|.....|..|.|..:|.|   |...|...|...||:
Yeast   634 ------GKPW---GCGKKFARSDALGRHFKTESGRRCITPLYEEARQEKSGQES 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	29/85 (34%)
		C2H2 Zn finger	294..314	CDD:275368	9/19 (47%)
		zf-H2C2_2	306..331	CDD:290200	14/24 (58%)
		C2H2 Zn finger	322..342	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	2/19 (11%)
		zf-H2C2_2	362..385	CDD:290200	3/22 (14%)
		C2H2 Zn finger	378..398	CDD:275368	6/19 (32%)
		zf-H2C2_2	390..415	CDD:290200	8/27 (30%)
		C2H2 Zn finger	406..426	CDD:275368	4/12 (33%)
		SIR2	<425..>465	CDD:294129
		C2H2 Zn finger	434..454	CDD:275368
		C2H2 Zn finger	461..482	CDD:275368
		C2H2 Zn finger	490..509	CDD:275368
		lambda-1	491..>603	CDD:212564
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
CRZ1	NP_014371.1	COG5048	139..617	CDD:227381	33/102 (32%)
		C2H2 Zn finger	571..591	CDD:275368	9/19 (47%)
		C2H2 Zn finger	599..619	CDD:275368	8/19 (42%)
		C2H2 Zn finger	627..655	CDD:275368	8/46 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100