DRSC/TRiP Functional Genomics Resources

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Protein Alignment cg and ZNF444

DIOPT Version :9

Sequence 1:NP_001097306.2 Gene:cg / 36571 FlyBaseID:FBgn0000289 Length:837 Species:Drosophila melanogaster
Sequence 2:NP_060807.2 Gene:ZNF444 / 55311 HGNCID:16052 Length:327 Species:Homo sapiens


Alignment Length:186 Identity:63/186 - (33%)
Similarity:82/186 - (44%) Gaps:41/186 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   250 DSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVH 314
            |||...| .|.||.:..|:|           ...|.:......||.||||:.|...||..|.:.|
Human   149 DSQAVRP-YKQEPSSPPLAP-----------GLPAFLAAPGTTSCPECGKTSLKPAHLLRHRQSH 201

  Fly   315 TGERPHICTHCGKSFAHKHCLNTHLLLHSTE--------RPYQCQECKKSFTLKHHLLTHSRVHS 371
            :||:||.|..|||:|..|..|..|...|...        ||                     :.:
Human   202 SGEKPHACPECGKAFRRKEHLRRHRDTHPGSPGSPGPALRP---------------------LPA 245

  Fly   372 RERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHG 427
            ||:|..|.|||:.|..:.|||.|.|.|:|.||:.|.|||:.|.:..|::.|.|.||
Human   246 REKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIHG 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cgNP_001097306.2 COG5048 287..>371 CDD:227381 26/91 (29%)
C2H2 Zn finger 294..314 CDD:275368 9/19 (47%)
zf-H2C2_2 306..331 CDD:290200 13/24 (54%)
C2H2 Zn finger 322..342 CDD:275368 8/19 (42%)
C2H2 Zn finger 350..370 CDD:275368 0/19 (0%)
zf-H2C2_2 362..385 CDD:290200 7/22 (32%)
C2H2 Zn finger 378..398 CDD:275368 10/19 (53%)
zf-H2C2_2 390..415 CDD:290200 14/24 (58%)
C2H2 Zn finger 406..426 CDD:275368 8/19 (42%)
SIR2 <425..>465 CDD:294129 2/3 (67%)
C2H2 Zn finger 434..454 CDD:275368
C2H2 Zn finger 461..482 CDD:275368
C2H2 Zn finger 490..509 CDD:275368
lambda-1 491..>603 CDD:212564
C2H2 Zn finger 575..595 CDD:275368
C2H2 Zn finger 720..740 CDD:275368
C2H2 Zn finger 752..771 CDD:275368
ZNF444NP_060807.2 SCAN 21..98 CDD:366881
PRK14959 <60..>182 CDD:184923 11/44 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 101..171 9/33 (27%)
COG5048 <179..>280 CDD:227381 43/121 (36%)
C2H2 Zn finger 181..201 CDD:275368 9/19 (47%)
C2H2 Zn finger 209..229 CDD:275368 8/19 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 220..243 5/43 (12%)
C2H2 Zn finger 252..272 CDD:275368 10/19 (53%)
zf-C2H2 278..300 CDD:333835 8/21 (38%)
C2H2 Zn finger 280..300 CDD:275368 8/19 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..327
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S6326
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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