DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cg and CG1792

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	80/323 - (24%)
Similarity:	127/323 - (39%)	Gaps:	87/323 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 EECNEILIKRAIAAGHHQTHTITAADGSHHHASGG-----TPSFCS----------------VGG 222
            ||.|.:::        ||...:|..     ...||     .|..||                :..
  Fly    23 EEPNSVML--------HQIEVLTGL-----FLLGGPGNELPPFICSPCELDLQTAIAFRERVIRT 74

  Fly   223 ATTL-----LG--DILPGISVQVQKVIQG------------------LEDNED-----SQGEAPN 257
            ..||     ||  :::...:|.|:|.||.                  ||:.|:     .|.|.|.
  Fly    75 QKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQNEQPQ 139

  Fly   258 LKL--EPGTLELSPKT--ELQESMHFSE-TDAT--------------IKKE---RPYSCDECGKS 300
            :|:  :...|..|.||  .:..|:.|:: :.||              :|:|   |...|::||:.
  Fly   140 VKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGRH 204

  Fly   301 FLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLT 365
            |....:...|...|||.:...|..|.:.|.....|..|..||:....:||:.|:.:::.....:.
  Fly   205 FTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQ 269

  Fly   366 HSRV-HSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHG 427
            |.|: |:..:||.|:||.::|.:...|.||...|.|.|.:.|:.|..||.:.:||..|.|..|
  Fly   270 HERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKG 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	23/87 (26%)
		C2H2 Zn finger	294..314	CDD:275368	5/19 (26%)
		zf-H2C2_2	306..331	CDD:290200	7/24 (29%)
		C2H2 Zn finger	322..342	CDD:275368	5/19 (26%)
		C2H2 Zn finger	350..370	CDD:275368	4/20 (20%)
		zf-H2C2_2	362..385	CDD:290200	8/23 (35%)
		C2H2 Zn finger	378..398	CDD:275368	7/19 (37%)
		zf-H2C2_2	390..415	CDD:290200	10/24 (42%)
		C2H2 Zn finger	406..426	CDD:275368	8/19 (42%)
		SIR2	<425..>465	CDD:294129	1/3 (33%)
		C2H2 Zn finger	434..454	CDD:275368
		C2H2 Zn finger	461..482	CDD:275368
		C2H2 Zn finger	490..509	CDD:275368
		lambda-1	491..>603	CDD:212564
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	13/69 (19%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	4/20 (20%)
		zf-C2H2	281..303	CDD:278523	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	7/19 (37%)
		zf-H2C2_2	296..320	CDD:290200	10/23 (43%)
		C2H2 Zn finger	311..329	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100