DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cg and scrt2

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_998802.1	Gene:	scrt2 / 325372	ZFINID:	ZDB-GENE-030131-4097	Length:	312	Species:	Danio rerio

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	86/177 - (48%)	Gaps:	28/177 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 KTELQESMHFSETDATIKKE--------RPYSCDECGKSFLLKHHLTTHARVH---TGERPHICT 323
            |.|:.|:....|    ::||        ..::|:||||::....:|:.|.:.|   ..:....|.
Zfish   136 KGEVSEAAKADE----VEKEVVGVNNGGARHTCNECGKTYATSSNLSRHKQTHRSLDSKMARKCP 196

  Fly   324 HCGKSFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFP-- 386
            .|.|.:.....|..|:|.|..:  ::|..|.|:|:....|..|.|.|:.|:||.|..||:||.
Zfish   197 TCDKVYVSMPALAMHILTHDLK--HKCHVCSKAFSRPWLLQGHMRSHTGEKPFACAHCGKAFADR 259

  Fly   387 --LKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMH---SRFHGS 428
              |:.|:.|||.|    :.|.|:.|.::||.:::|..|   :.|.||
Zfish   260 SNLRAHMQTHSAF----KHYSCKRCNKTFALKSYLNKHYESACFRGS 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	24/94 (26%)
		C2H2 Zn finger	294..314	CDD:275368	7/19 (37%)
		zf-H2C2_2	306..331	CDD:290200	6/27 (22%)
		C2H2 Zn finger	322..342	CDD:275368	6/19 (32%)
		C2H2 Zn finger	350..370	CDD:275368	7/19 (37%)
		zf-H2C2_2	362..385	CDD:290200	10/22 (45%)
		C2H2 Zn finger	378..398	CDD:275368	10/23 (43%)
		zf-H2C2_2	390..415	CDD:290200	9/24 (38%)
		C2H2 Zn finger	406..426	CDD:275368	6/22 (27%)
		SIR2	<425..>465	CDD:294129	3/4 (75%)
		C2H2 Zn finger	434..454	CDD:275368
		C2H2 Zn finger	461..482	CDD:275368
		C2H2 Zn finger	490..509	CDD:275368
		lambda-1	491..>603	CDD:212564
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
scrt2	NP_998802.1	zf-C2H2	162..184	CDD:278523	7/21 (33%)
		C2H2 Zn finger	164..184	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..212	CDD:275371	4/16 (25%)
		COG5048	219..>295	CDD:227381	29/79 (37%)
		zf-C2H2	219..241	CDD:278523	7/21 (33%)
		C2H2 Zn finger	221..241	CDD:275368	7/19 (37%)
		zf-H2C2_2	234..257	CDD:290200	11/22 (50%)
		zf-C2H2	247..269	CDD:278523	8/21 (38%)
		C2H2 Zn finger	249..269	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..293	CDD:275368	5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910