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Protein Alignment cg and ZNF544

DIOPT Version :10

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_001374339.1	Gene:	ZNF544 / 27300	HGNCID:	16759	Length:	769	Species:	Homo sapiens

Alignment Length:	833	Identity:	205/833 - (24%)
Similarity:	319/833 - (38%)	Gaps:	246/833 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCAAQNPPPFGYTWGFADN-----GNRAAESVLEISPNINYTVSG-ESMPYLLSTDGSLAVQKDV 59
            :|.|:...|..:.....:|     .:||.|   |:|.::....|| |..|.|:     |...:|.
Human   126 LCRAEQEAPRDWKATLEENRLNSEKDRARE---ELSHHVEVYRSGPEEPPSLV-----LGKVQDQ 182

  Fly    60 KGLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGG----------------ASTVVKKQDNNQQV 108
            .......:.|.:|.|.:.::..|.......:..||                .||...|.  |.||
Human   183 SNQLREHQENSLRFMVLTSERLFAQREHCELELGGGYSLPSTLSLLPTTLPTSTGFPKP--NSQV 245

  Fly   109 LSLDKNYLLVDPATAAAAAAAAGGDSGLAHHHTLTNGSIVDAKTGQTVLTAGSAAAKSHFSSIGA 173
            ..|.:|                   |...:|.  .||:  |.|..::...|.:.....:.|.:|.
Human   246 KELKQN-------------------SAFINHE--KNGA--DGKHCESHQCARAFCQSIYLSKLGN 287

  Fly   174 LHLTQEECNEILIK-RAIAAG-----HHQTHTITAADGSHHHASGGTPSFCSVGGATTLLGDILP 232
            :...::...|.::. .::..|     |.:|.::..:|....:                  |::..
Human   288 VETGKKNPYEYIVSGDSLNYGSSLCFHGRTFSVKKSDDCKDY------------------GNLFS 334

  Fly   233 -GISVQVQKVIQG--------------------LEDNEDSQGEAPNLKLEPGTLELSPKTELQES 276
             .:|:..||.:..                    ::......||.| .:.|    |......:..|
Human   335 HSVSLNEQKPVHFGKSQYECDECRETCSESLCLVQTERSGPGETP-FRCE----ERCAAFPMASS 394

  Fly   277 MHFSETDATIKKERPYSCDECGKSF----LLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNT 337
              ||:.:.....|:|..|::|||||    |:      |.|.||||:|..||.|||||:..:.|..
Human   395 --FSDCNIIQTTEKPSVCNQCGKSFSCCKLI------HQRTHTGEKPFECTQCGKSFSQSYDLVI 451

  Fly   338 HLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGER 402
            |...|:.|:||:|..|.||||.:..|:||.|:|:.|:|:.|.||.::|....:|:.|.:.|.||:
Human   452 HQRTHTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIHTGEK 516

  Fly   403 PYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIH-GKIPHSCTVCGK 466
            ||.|..||:||:|...|:.|.|.|....||.|.:||.||.:|:.||.|.|.| |:.|:.|.:|||
Human   517 PYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGK 581

  Fly   467 EFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAEL--HQHVRTAHNGVNPNTSSATIIANQQL 529
            .|.|...|::| :|:||||:.:.|:.||:.|...:.|  ||.:   |.|..|...:.   ..:..
Human   582 SFSQSSKLITH-QRIHTGEKPYQCIECGKSFRWNSNLVIHQRI---HTGEKPYDCTH---CGKSF 639

  Fly   530 QQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRL 594
            .|::...|.::||                         .....:.|.|||.|||....|..||::
Human   640 SQSYQLVAHKRTH-------------------------TGEKPYECNECGKAFNRSTQLIRHLQI 679

  Fly   595 HTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQ 659
            |||:|....:.|....|                                  .|:..||.|.|
Human   680 HTGEKPYKCNQCNKAFA----------------------------------RSSYLVMHQRT--- 707

  Fly   660 AANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPANKPKSHFCASCG 724
                                       |..:                         |...|:.||
Human   708 ---------------------------HTGE-------------------------KPFECSQCG 720

  Fly   725 KGFAAKHGLMQHNRRHPNGGCTVRTHVC-ECGKAFFQKNHLMLHQRQHLETKP 776
            |.|:....|:.|:|.|..    .:.:.| :|||:|.|::.|::|:|.|...||
Human   721 KAFSGSSNLLSHHRIHSG----EKPYECSDCGKSFRQQSQLVVHRRTHTGEKP 769

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.