DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cg and Zfp772

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_663552.2	Gene:	Zfp772 / 232855	MGIID:	2385265	Length:	416	Species:	Mus musculus

Alignment Length:	371	Identity:	125/371 - (33%)
Similarity:	185/371 - (49%)	Gaps:	50/371 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 LTQEECNEILIKRA----IAAGHHQTHTITAADGSHHHASGGTPSFCSVGGATTLLGDILPGISV 236
            |.|...:|||...:    |.:|.|:...:         .|.|.||       ...|..:.||..:
Mouse    66 LYQTVMSEILTLMSSLGLIPSGIHEMTQL---------KSWGEPS-------VPALRFLTPGCWI 114

  Fly   237 QVQKVIQGLEDNEDSQGEAPNLK-------LEPGTLELSPKTELQES----------------MH 278
            :|...:...|.:..::|..|:..       .|...|.:.....||.|                |:
Mouse   115 KVDSEMSPFEQSPSAEGARPSTLQQHMLCCAETPVLSMDNVMILQTSSGLLRHQVTYNVGDAPMN 179

  Fly   279 FSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHS 343
            ....:|...:::...|.:|||:|....||..|..:||||:|..|:.||.||:.|..|..|..:|:
Mouse   180 MESGEAIQSEKKNCICSDCGKTFTSTSHLNRHRMIHTGEKPFQCSECGMSFSQKAFLIKHFRIHT 244

  Fly   344 TERPYQCQECKKSFTLKHH--LLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVC 406
            .|:|::|.||.|:|  ||:  |::|.|||:.|.||.|.|||:::..:.:|..|.:.||.|:||.|
Mouse   245 GEKPFRCGECGKAF--KHNISLVSHQRVHTGETPFTCTECGKSYMTRSNLTRHFQVHAAEKPYSC 307

  Fly   407 EECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIH-GKIPHSCTVCGKEFLQ 470
            .|||::|.:::.||.|:|.|....||.|:|||.||.:|..|:.|.||| |:.|..|:.|||.|..
Mouse   308 SECGKAFKEKSSLIYHARVHTRERPFQCSECGKSFSQKAFLIKHFRIHTGEKPFRCSECGKTFKH 372

  Fly   471 KRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNP 516
            ...||:| :||||||....|..||:.::.::.|..|.| .|.|..|
Mouse   373 NCFLVAH-QRVHTGETPFTCTECGKSYMNRSSLLYHYR-VHTGEKP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	35/85 (41%)
		C2H2 Zn finger	294..314	CDD:275368	8/19 (42%)
		zf-H2C2_2	306..331	CDD:290200	13/24 (54%)
		C2H2 Zn finger	322..342	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	10/21 (48%)
		zf-H2C2_2	362..385	CDD:290200	12/24 (50%)
		C2H2 Zn finger	378..398	CDD:275368	6/19 (32%)
		zf-H2C2_2	390..415	CDD:290200	12/24 (50%)
		C2H2 Zn finger	406..426	CDD:275368	9/19 (47%)
		SIR2	<425..>465	CDD:294129	18/40 (45%)
		C2H2 Zn finger	434..454	CDD:275368	10/19 (53%)
		C2H2 Zn finger	461..482	CDD:275368	9/20 (45%)
		C2H2 Zn finger	490..509	CDD:275368	5/18 (28%)
		lambda-1	491..>603	CDD:212564	8/26 (31%)
		C2H2 Zn finger	575..595	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
Zfp772	NP_663552.2	KRAB	42..102	CDD:214630	12/51 (24%)
		KRAB	42..81	CDD:279668	5/14 (36%)
		COG5048	<191..344	CDD:227381	68/154 (44%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		zf-C2H2	195..215	CDD:278523	8/19 (42%)
		zf-H2C2_2	207..232	CDD:290200	13/24 (54%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		zf-H2C2_2	236..260	CDD:290200	10/25 (40%)
		C2H2 Zn finger	251..271	CDD:275368	10/21 (48%)
		zf-H2C2_2	263..286	CDD:290200	12/22 (55%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..315	CDD:290200	11/23 (48%)
		C2H2 Zn finger	307..327	CDD:275368	9/19 (47%)
		zf-H2C2_2	319..344	CDD:290200	13/24 (54%)
		COG5048	331..>391	CDD:227381	30/60 (50%)
		C2H2 Zn finger	335..355	CDD:275368	10/19 (53%)
		zf-H2C2_2	348..372	CDD:290200	12/23 (52%)
		C2H2 Zn finger	363..383	CDD:275368	9/20 (45%)
		zf-H2C2_2	376..398	CDD:290200	12/22 (55%)
		C2H2 Zn finger	391..411	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000