DRSC/TRiP Functional Genomics Resources

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Protein Alignment cg and mtf1

DIOPT Version :9

Sequence 1:NP_001097306.2 Gene:cg / 36571 FlyBaseID:FBgn0000289 Length:837 Species:Drosophila melanogaster
Sequence 2:XP_021322285.1 Gene:mtf1 / 195821 ZFINID:ZDB-GENE-020424-1 Length:749 Species:Danio rerio


Alignment Length:570 Identity:137/570 - (24%)
Similarity:208/570 - (36%) Gaps:164/570 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   222 GATTLLGD------------ILPGISVQVQKVIQGLEDNEDSQGEAPNLK-LEPGTLEL---SPK 270
            |:...:||            |.|.   |:|.:|        :.|..|..: :|..||.|   .|:
Zfish   116 GSLAFMGDPDGMSQGYIHHTISPD---QIQFII--------NPGSTPMPRNIEGATLTLHSECPE 169

  Fly   271 TELQESMHFSETDATIKKERPYSC--DECGKSFLLKHHLTTHARVHTGERPHICTH--CGKSFAH 331
            |:.:|          :|:   |.|  :.|.:::....:|.||.:.|.||...:|..  |||:|..
Zfish   170 TKQRE----------VKR---YQCLFEGCTRTYSTAGNLRTHQKTHRGEYTFVCNQQGCGKAFLT 221

  Fly   332 KHCLNTHLLLHSTERPYQC--QECKKSFTLKHHLLTHSRVHSRERPFVCQE--CGRAFPLKRHLV 392
            .:.|..|:.:|:.|:|::|  |.|:|:|...:.|..|.|:|: .:.|.|:.  |.:.|.....|.
Zfish   222 SYSLKIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHT-GKTFNCESEGCTKYFTTLSDLR 285

  Fly   393 THSKFHAGERPYVCEE--CGESFAQENHLIMHSRFHGSLNPFVCAE--CGASFPRKFQLVNHGRI 453
            .|.:.|.||:|:.|:.  ||::||..:||..|.|.|....||.|..  |..:|..::.|.:|.|.
Zfish   286 KHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGEKPFFCPSDGCEKTFSSQYSLKSHIRG 350

  Fly   454 HGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHP---------CVSCGEGFLTKAELHQHVRT 509
            |.|.| |.||                      .:||         |:|......|.:||.::   
Zfish   351 HDKGP-SFTV----------------------SSHPLSEDANHSLCLSDLSLISTDSELQEN--- 389

  Fly   510 AHNGVNPNTSSATIIANQQLQ-QAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDAN-GVARPQ 572
             ||....:.:|.|.|...:|. |:..:...:.....|.::..:.|.......:..||: ..|.||
Zfish   390 -HNSQGLDLNSVTPIRIFELMFQSPENSVSEDDPKPTESLAESFGLEPSPQTAPADASTHPAFPQ 453

  Fly   573 FVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQ 637
            .....|.|:                        |::||  |.....|    |.|...|.|..|..
Zfish   454 PPPSTCSSS------------------------CSITA--PAQDAQT----PPTTQQAPPPAVSS 488

  Fly   638 S-----------------------------------PVPVQIISSTGQVMSQTTLVQAA-NSTHP 666
            |                                   ||.....:|...|.:.|..|.|| ..|.|
Zfish   489 SSQTSSFPSAPPSSSQPAEVSSPSAPSATQHYMMAQPVSSPSAASVSSVPAGTAEVTAAVTHTVP 553

  Fly   667 QAVVTAVPTMPVHGQQ-------QHLQHVAQQQQQQQQQQQQQQQHVVSV 709
            .|....:...|..|.|       |:||.:.......||..:||...|..|
Zfish   554 LAAPPTISIAPTLGLQPSLVMSDQNLQWILSSAASAQQNPEQQGPKVEKV 603

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cgNP_001097306.2 COG5048 287..>371 CDD:227381 28/89 (31%)
C2H2 Zn finger 294..314 CDD:275368 5/21 (24%)
zf-H2C2_2 306..331 CDD:290200 11/26 (42%)
C2H2 Zn finger 322..342 CDD:275368 7/21 (33%)
C2H2 Zn finger 350..370 CDD:275368 8/21 (38%)
zf-H2C2_2 362..385 CDD:290200 7/24 (29%)
C2H2 Zn finger 378..398 CDD:275368 5/21 (24%)
zf-H2C2_2 390..415 CDD:290200 10/26 (38%)
C2H2 Zn finger 406..426 CDD:275368 9/21 (43%)
SIR2 <425..>465 CDD:294129 15/41 (37%)
C2H2 Zn finger 434..454 CDD:275368 6/21 (29%)
C2H2 Zn finger 461..482 CDD:275368 2/20 (10%)
C2H2 Zn finger 490..509 CDD:275368 5/18 (28%)
lambda-1 491..>603 CDD:212564 20/113 (18%)
C2H2 Zn finger 575..595 CDD:275368 2/19 (11%)
C2H2 Zn finger 720..740 CDD:275368
C2H2 Zn finger 752..771 CDD:275368
mtf1XP_021322285.1 C2H2 Zn finger 183..202 CDD:275368 4/18 (22%)
COG5048 <185..349 CDD:227381 53/164 (32%)
C2H2 Zn finger 210..232 CDD:275368 7/21 (33%)
C2H2 Zn finger 240..262 CDD:275368 8/21 (38%)
C2H2 Zn finger 272..291 CDD:275368 4/18 (22%)
C2H2 Zn finger 299..321 CDD:275368 9/21 (43%)
COG5048 302..>431 CDD:227381 38/155 (25%)
C2H2 Zn finger 329..351 CDD:275368 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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