DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cg and znf-782

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	601	Identity:	146/601 - (24%)
Similarity:	215/601 - (35%)	Gaps:	213/601 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 QEECNEIL--------IKRAIAAGHHQTHTITAADGSHHHASGGTPSFCSVGGATTLLGDILPGI 234
            :||.:|.|        ....::||  ..|..::::|||    |.:|
Worm    40 EEEFDEELEELENSDSASSLVSAG--SPHGSSSSNGSH----GSSP------------------- 79

  Fly   235 SVQVQKVIQGLEDNEDSQGEAPNLKL----EPGTLELSPKTELQESMHFSETDATIKKERPYSCD 295
            .:|||...||...:....|:.....:    ..|....|    :.||...|.|.     |:||:|.
Worm    80 PLQVQSPSQGSGSSGSPTGQPEKRHICTVCGKGFSYFS----ILESHKRSHTG-----EKPYNCH 135

  Fly   296 ECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFA-------HK--------------------- 332
            .|.|:|..|..|..|.|.||||||:.|.:|.|:||       |:
Worm   136 FCQKTFAQKATLQVHERTHTGERPYKCRYCEKTFAQYGTKTVHEKSAHLGIRNYKCPKCDKLLSS 200

  Fly   333 -HCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTH-SRVHSR-ERPFVCQECGRAFPLKRHLVTH 394
             ..|.||...|. ::.::|..|.|:|.||::|..| .:||.: ||..||..|.:.|.....|..|
Worm   201 PSALYTHKKTHG-DKTFRCDFCPKTFALKNYLKLHVKQVHEQNERKHVCVYCNKGFAYAGSLQVH 264

  Fly   395 SKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPH 459
            .:.|.|||||||:.|.::||.:.:|..|.|.|....|:.|..|..:|.:|.||..|...|....|
Worm   265 VRTHTGERPYVCKFCPKAFASQGNLQSHERTHTGERPYSCQFCQRTFIQKSQLTAHESTHLTQKH 329

  Fly   460 S---------------------------CTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGF 497
            |                           ||.|.|::....:|..|||: ||.:.|:.|..||:.:
Worm   330 SVNPDSTTADILPVAGSVTDHQMVGNYECTFCNKKYPYASSLYIHMRK-HTEKSAYSCDGCGKPY 393

  Fly   498 LTKAELHQHVRTAHNGVNPNTSSATIIANQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVST 562
            ..|..|:.|                    |...:|..::                       :.|
Worm   394 SQKISLNIH--------------------QDQCEAFKNR-----------------------LKT 415

  Fly   563 TDANGVARPQFV--CRECGSAFNSREALALH------------LRL-------HTGDKSLMTD-- 604
            ||:      ||.  |..||.:|..|.||.:|            |:|       ...|....|:
Worm   416 TDS------QFSHNCDGCGKSFVQRIALQIHVDSCEPHKNLARLKLSQQQNQNQNSDSESDTEMK 474

  Fly   605 LCALTAALPGHFLSTASLNPGTVVTANP---------NLVGQSPVPVQIISSTGQVMSQTTLVQA 660
            :|.|               |...:|..|         |:..|.|.|    :..|.::..|:|.
Worm   475 ICPL---------------PNPPLTLAPTHQQIPPPVNIYAQQPPP----NPLGSILGNTSLT-- 518

  Fly   661 ANSTHPQAVVTAVPTM 676
                 ||.:...:|::
Worm   519 -----PQTLNFGLPSL 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	36/113 (32%)
		C2H2 Zn finger	294..314	CDD:275368	8/19 (42%)
		zf-H2C2_2	306..331	CDD:290200	14/31 (45%)
		C2H2 Zn finger	322..342	CDD:275368	9/48 (19%)
		C2H2 Zn finger	350..370	CDD:275368	8/20 (40%)
		zf-H2C2_2	362..385	CDD:290200	9/24 (38%)
		C2H2 Zn finger	378..398	CDD:275368	5/19 (26%)
		zf-H2C2_2	390..415	CDD:290200	12/24 (50%)
		C2H2 Zn finger	406..426	CDD:275368	7/19 (37%)
		SIR2	<425..>465	CDD:294129	14/66 (21%)
		C2H2 Zn finger	434..454	CDD:275368	7/19 (37%)
		C2H2 Zn finger	461..482	CDD:275368	8/20 (40%)
		C2H2 Zn finger	490..509	CDD:275368	6/18 (33%)
		lambda-1	491..>603	CDD:212564	23/132 (17%)
		C2H2 Zn finger	575..595	CDD:275368	10/38 (26%)
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	4/23 (17%)
		zf-H2C2_2	119..143	CDD:290200	11/28 (39%)
		C2H2 Zn finger	134..154	CDD:275368	8/19 (42%)
		zf-H2C2_2	147..171	CDD:290200	13/23 (57%)
		C2H2 Zn finger	162..180	CDD:275368	6/17 (35%)
		COG5048	<187..404	CDD:227381	65/238 (27%)
		C2H2 Zn finger	191..211	CDD:275370	3/19 (16%)
		C2H2 Zn finger	218..239	CDD:275368	8/20 (40%)
		C2H2 Zn finger	248..268	CDD:275368	5/19 (26%)
		zf-H2C2_2	260..285	CDD:290200	12/24 (50%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		zf-H2C2_2	288..313	CDD:290200	8/24 (33%)
		C2H2 Zn finger	304..324	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..403	CDD:275368	6/36 (17%)
		C2H2 Zn finger	424..441	CDD:275368	7/16 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000